Results 71 to 80 of about 9,239,414 (293)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Principal bundle structure of matrix manifolds

open access: yes, 2017
In this paper, we introduce a new geometric description of the manifolds of matrices of fixed rank. The starting point is a geometric description of the Grassmann manifold $\mathbb{G}_r(\mathbb{R}^k)$ of linear subspaces of dimension ...
Billaud-Friess, Marie   +2 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Transformation of Islamic Education Viewed From The Influence of Leadership Style, Managerial Cognitive Capability, and Job Satisfaction on The Organizational Commitment of Principals in Asahan District

open access: yesEdukasi Islami: Jurnal Pendidikan Islam
This research aims to determine the transformation of Islamic education in terms of the influence of leadership style, managerial cognitive abilities, and job satisfaction on the organizational commitment of elementary school (SD) principals in Asahan ...
Suwastati Sagala   +2 more
doaj   +1 more source

Contact structures on principal circle bundles

open access: yes, 2011
We describe a necessary and sufficient condition for a principal circle bundle over an even-dimensional manifold to carry an invariant contact structure.
Ding, Fan, Geiges, Hansjörg
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The perspectives of beginner principals on their new roles in school leadership and management: A South African case study

open access: yesSouth African Journal of Education, 2020
In the study reported on here we aimed to explore how beginner principals perceived their roles as new appointees. School principals are expected to demonstrate proficiency when performing leadership and management roles in schools.
Malesela Gilbert Sepuru   +1 more
doaj   +1 more source

N-Dimensional Principal Component Analysis [PDF]

open access: yes, 2010
In this paper, we first briefly introduce the multidimensional Principal Component Analysis (PCA) techniques, and then amend our previous N-dimensional PCA (ND-PCA) scheme by introducing multidirectional decomposition into ND-PCA implementation.
Yu, Hongchuan
core  

On motivic principal value integrals

open access: yes, 2006
Inspired by p-adic (and real) principal value integrals, we introduce motivic principal value integrals associated to multi-valued rational differential forms on smooth algebraic varieties.
Arnold   +9 more
core   +1 more source

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