Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Principal Components for Practice-Oriented Measurement of Running Technique: A Proof-Of-Concept Study. [PDF]
Debertin D +3 more
europepmc +1 more source
Detecting gene-gene interactions from GWAS using diffusion kernel principal components. [PDF]
Walakira A +6 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Principal components-based selection criteria for genetic improvement of growth in sheep breeding programs. [PDF]
Mandal A +4 more
europepmc +1 more source
Competitive and Recreational Running Kinematics Examined Using Principal Components Analysis. [PDF]
Quan W +5 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
DAPCy: a Python package for the discriminant analysis of principal components method for population genetic analyses. [PDF]
Correa Rojo A +4 more
europepmc +1 more source
Physiological and Somatic Principal Components Determining VO2max in the Annual Training Cycle of Endurance Athletes. [PDF]
Grzebisz-Zatońska N +4 more
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

