We estimated local ancestry on the autosomes and X chromosome in a large US-based study of 12,793 Hispanic/Latino individuals using the RFMix method, and we compared different reference panels and approaches to local ancestry estimation on the X ...
Sharon R. Browning +8 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
On the Construct Validity of the Reading Section of the University of Tehran English Proficiency Test [PDF]
University of Tehran administers a test known as The University of Tehran English Proficiency Test (the UTEPT) to PhD candidates on a yearly basis. By definition, the test can be considered a high-stakes one. The validity of high stakes tests needs to be
Mohammad Salehi
doaj
The metabolic spatial covariance pattern of definite idiopathic normal pressure hydrocephalus: an FDG PET study with principal components analysis. [PDF]
Rau A +6 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Initial Steps towards a Multilevel Functional Principal Components Analysis Model of Dynamical Shape Changes. [PDF]
Farnell DJJ, Claes P.
europepmc +1 more source
A Bicluster-Based Bayesian Principal Component Analysis Method for Microarray Missing Value Estimation [PDF]
Fanchi Meng, Cheng Cai, Hong Yan
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Author Correction: mbDenoise: microbiome data denoising using zero-inflated probabilistic principal components analysis. [PDF]
Zeng Y, Li J, Wei C, Zhao H, Wang T.
europepmc +1 more source

