Results 71 to 80 of about 2,140,628 (292)

A Simple Solution and Dilatancy Characterization for a Circular Tunnel Excavated in the Nonlinear Strain-Softening and Nonlinear Dilatancy Rock Mass

open access: yesAdvances in Civil Engineering, 2023
Tunnel opening or excavation in the strain-softening rock masses primarily leads to initial stress release and rock deformation. The increasing plastic shear strain induces a nonlinear variation of dilatancy in rock masses. Therefore, tunnel stability is
Xiuling Wang
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Microstructure and mechanical properties of CoCrNiVAlx multi-principal component alloy

open access: yesJournal of Materials Research and Technology
Multi-principal component alloy has been proved to form disordered solid solution in most cases. However, multi-principal component alloy with single phase solid solution has a few disadvantages in mechanical properties, such as low strength or poor ...
Yuzhi Shi   +8 more
doaj   +1 more source

Principal matrix solutions and variation of parameters for a Volterra integro-differential equation and its adjoint

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2006
We define the principal matrix solution $Z(t,s)$ of the linear Volterra vector integro-differential equation \[ x'(t) = A(t)x(t) + \int_s^t B(t,u)x(u)\,du \] in the same way that it is defined for $x' = A(t)x$ and prove that it is the unique matrix ...
Leigh Becker
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Assessing the Structure of the Ways of Coping Questionnaire in Fibromyalgia Patients Using Common Factor Analytic Approaches

open access: yesPain Research and Management, 2016
The Ways of Coping Questionnaire (WCQ) is a widely used measure of coping processes. Despite its use in a variety of populations, there has been concern about the stability and structure of the WCQ across different populations.
Charles Van Liew   +4 more
doaj   +1 more source

Lateral/Basolateral Amygdala Serotonin Type-2 Receptors Modulate Operant Self-administration of a Sweetened Ethanol Solution via Inhibition of Principal Neuron Activity

open access: yesFrontiers in Integrative Neuroscience, 2014
The lateral/basolateral amygdala (BLA) forms an integral part of the neural circuitry controlling innate anxiety and learned fear. More recently, BLA dependent modulation of self-administration behaviors suggests a much broader role in the regulation of
Brian eMccool   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A New Unified Solution for Circular Tunnel Based on a Four-Stage Constitutive Model considering the Intermediate Principal Stress

open access: yesAdvances in Civil Engineering, 2018
Based on the triaxial test, the elasto-perfectly plastic strain-softening damage model (EPSDM) is proposed as a new four-stage constitutive model. Compared with traditional models, such as the elasto-brittle-plastic model (EBM), elasto-strain-softening ...
Liang Chen   +5 more
doaj   +1 more source

Gauge theory in dimension $7$

open access: yes, 2009
We first review the notion of a $G_2$-manifold, defined in terms of a principal $G_2$ ("gauge") bundle over a $7$-dimensional manifold, before discussing their relation to supergravity. In a second thread, we focus on associative submanifolds and present
Frederik Witt   +4 more
core   +1 more source

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