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Socrates, Vlastos, Scanlon and the Principle of the Sovereignty of Virtue
This article offers a new formulation of the Socratic principle known as the Principle of the Sovereignty of Virtue (PSV). It is divided in three sections. In the first section I criticize Vlastos’ formulation of the PSV.
Daniel Simão Nascimento
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Sufficient reason and reason enough [PDF]
I offer an analysis of the Principle of Sufficient Reason and its relevancy for the scientific endeavour. I submit that the world is not, and cannot be, rational—only some brained beings are.
Romero, Gustavo E. +2 more
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Alexander Baumgarten on the Principle of Sufficient Reason [PDF]
This paper defends the Principle of Sufficient Reason, taking Baumgarten as its guide. The primary aim is not to vindicate the principle, but rather to explore the kinds of resources Baumgarten originally thought sufficient to justify the PSR against its
Fugate, Courtney D.
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Antinomies and the Principle of Sufficient Reason [PDF]
As concerns proofs of "Transcendental Antinomies" in the Critique of Pure Reason, it has been quite a natural attitude to entertain doubts against their validity. This paper picks up some proofs from both Theses and Antitheses of the Antinomies and tries
長田, 蔵人
core
Background: Arthur Schopenhauer’s On the Fourfold Root of the Principle of Sufficient Reason (in its revised 1847 edition) has been variously interpreted as an epistemological prelude to his metaphysics of will, as a continuation of Kantian ...
Jan Kerkmann
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Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Retrocausal Effects as a Consequence of Quantum Mechanics Refined to Accommodate the Principle of Sufficient Reason [PDF]
The principle of sufficient reason asserts that anything that happens does so for a reason: no definite state of affairs can come into being unless there is a sufficient reason why that particular thing should happen. This principle is usually attributed
Daniel P. Sheehan +2 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source

