Results 141 to 150 of about 97,942 (322)

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

Proceedings of the National Academy of Sciences of the United States of America, 1993
K. Pan, M. Baldwin, J. Nguyen, M. Gasset, A. Serban, D. Groth, I. Mehlhorn, Zehuan Huang, R. Fletterick, F. Cohen   +9 more
semanticscholar   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples

Prion
Prion disease is an infectious and fatal neurodegenerative disease. Western blotting (WB)-based identification of proteinase K (PK)-resistant prion protein (PrPres) is considered a definitive diagnosis of prion diseases. In this study, we aimed to detect
Sachiko Koyama, Kaoru Yagita, Hideomi Hamasaki, Hideko Noguchi, Masahiro Shijo, Kosuke Matsuzono, Kei-Ichiro Takase, Keita Kai, Shin-Ichi Aishima, Kyoko Itoh, Toshiharu Ninomiya, Naokazu Sasagasako, Hiroyuki Honda   +12 more
doaj   +1 more source

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains

, 2015
Christina D. Orrú, Bradley R. Groveman, Lynne D. Raymond, Andrew G. Hughson, Romolo Nonno, Wen‐Quan Zou, Bernardino Ghetti, Pierluigi Gambetti, Byron Caughey   +8 more
openalex   +2 more sources

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

International Journal of Cancer, Volume 158, Issue 6, Page 1755-1768, 15 March 2026.
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam, Xiaojun Zhang, Riajul Wahab, Md Mahedi Hasan, Shivaniben Dhadhal, Bowon Kang, Md Mynul Hassan, Mazharul Karim, Jeong Uk Choi, Muhit Rana, Jian‐Ying Zhang, Sourav Roy, Youngro Byun, In‐San Kim, Jae Yun Song, Eugene P. Toy, Sireesha Y. Reddy, Farzana Alam, Taslim A. Al‐Hilal   +18 more
wiley   +1 more source

Increased Borrelia burgdorferi Seroprevalence in Nova Scotia—Prevalence and Distribution 10 Years Later

Zoonoses and Public Health, Volume 73, Issue 2, Page 164-168, March 2026.
ABSTRACT Lyme disease (LD), a tick‐borne infection, is endemic in Nova Scotia. One decade ago, the seropositivity rate to Borrelia burgdorferi was 2/1855 (0.14%). In the current study, using residual sera representing ages 10–64 years, we demonstrate an increase in seroprevalence, to 25/1872 (1.60%), with the highest seroprevalence in the western area ...
Carrie Phillips, Colleen Jackson, Linda Passerini, Kathryn McIsaac, Courtney Loomer, Heather Coatsworth, Jennifer Cram, Elizabeth Simms, David Haldane, Todd F. Hatchette, Glenn Patriquin   +10 more
wiley   +1 more source

Evolution of transmissible spongiform encephalopathy and the prion protein gene ( PRNP ) in mammals [PDF]

, 2020
Brittaney L. Buchanan, Robert M. Zink
openalex   +1 more source

Prions [PDF]

Current Biology, 1999
openaire   +2 more sources

Prion liposomes [PDF]

Biochemical Journal, 1990
R, Gabizon, S B, Prusiner
openaire   +2 more sources

Mild Short‐Term Caloric Restriction Induces Coordinated Changes That Promote Lipid Deposition While Maintaining Thermogenesis Capacity in Interscapular Brown Adipose Tissue of Male Rats

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Rats under mild caloric restriction (85% vs. ad libitum) for 2 weeks show metabolic and structural adaptations in iBAT. Caloric restriction increases glycolysis and triglyceride deposition in the tissue, leading to larger lipid droplets. It also reduces mitochondrial iBAT content, while maintaining iBAT thermogenic potential thanks to an increased ...
Giuliana Panico, Vincenzo Migliaccio, Gabriella Pinto, Anna Iliano, Gianluca Fasciolo, Martina Coletta, Paola Venditti, Maria Moreno, Angela Amoresano, Pieter de Lange, Lillà Lionetti, Assunta Lombardi   +11 more
wiley   +1 more source