Results 231 to 240 of about 10,379,704 (316)

Prion Protein Endoproteolysis: Cleavage Sites, Mechanisms and Connections to Prion Disease. [PDF]

J Neurochem
Castle AR, Westaway D.
europepmc   +1 more source

Author Correction: In vivo base editing extends lifespan of a humanized mouse model of prion disease. [PDF]

Nat Med
An M, Davis JR, Levy JM, Serack FE, Harvey JW, Brauer PP, Pirtle CP, Berríos KN, Newby GA, Yeh WH, Kamath N, Mortberg M, Lian Y, Howard M, DeSouza-Lenz K, Guzman K, Thai A, Graffam S, Laversenne V, Coffey AA, Frei J, Pierce SE, Safar JG, Deverman BE, Minikel EV, Vallabh SM, Liu DR.   +26 more
europepmc   +1 more source

Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease.

Brain : a journal of neurology, 2016
L. Haas, Santiago V. Salazar, M. Kostylev, J. Um, Adam C. Kaufman, S. Strittmatter   +5 more
semanticscholar   +1 more source

In vivo base editing extends lifespan of a humanized mouse model of prion disease. [PDF]

Nat Med
An M, Davis JR, Levy JM, Serack FE, Harvey JW, Brauer PP, Pirtle CP, Berríos KN, Newby GA, Yeh WH, Kamath N, Mortberg M, Lian Y, Howard M, DeSouza-Lenz K, Guzman K, Thai A, Graffam S, Laversenne V, Coffey AA, Frei J, Pierce SE, Safar JG, Deverman BE, Minikel EV, Vallabh SM, Liu DR.   +26 more
europepmc   +1 more source

Prion disease tempo determined by host-dependent substrate reduction.

Journal of Clinical Investigation, 2014
C. Mays, Chae Kim, Tracy Haldiman, Jacques Q van der Merwe, A. Lau, Jing Yang, Jennifer Grams, M. D. Di Bari, R. Nonno, G. Telling, Qingzhong Kong, J. Langeveld, Debbie McKenzie, D. Westaway, J. Safar   +14 more
semanticscholar   +1 more source

Investigating the In Vivo Effects of Anti-Prion Protein Nanobodies on Prion Disease with AAV Vector. [PDF]

Pathogens
Zhang J, Wang M, Wang D, Zhang X, Ma Y, Pardon E, Steyaert J, Abskharon R, Wang F, Ma J.   +9 more
europepmc   +1 more source

TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease. [PDF]

Front Neurosci
Carpanini SM, Bradford BM, Alfieri A, Piccardo P, Monzón-Sandoval J, Brown D, Boyle A, Pokrovskaya A, Mabbott NA, Manson J, McColl BW.   +10 more
europepmc   +1 more source

Delayed progression of prion disease in mice by polyarginine-facilitated prevention of PrP^Sc propagation in the spleen. [PDF]

Neurotherapeutics
Lee S, Kim J, Lee Y, Yoo M, Kim J, Sohn HJ, Ryou C.   +6 more
europepmc   +1 more source

Prion disease and the 'protein-only hypothesis'.

Essays in Biochemistry, 2014
Jiyan Ma, Fei Wang
semanticscholar   +1 more source