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1996
Abstract Human prion diseases include idiopathic, genetic, and acquired disorders. Heterogeneous clinicopathologic features make diagnosis challenging. Accurate diagnosis requires a combined clinical, neuropathologic, genetic, and biochemical approach. Neuropathologic assessment is performed following autopsy in most cases.
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Abstract Human prion diseases include idiopathic, genetic, and acquired disorders. Heterogeneous clinicopathologic features make diagnosis challenging. Accurate diagnosis requires a combined clinical, neuropathologic, genetic, and biochemical approach. Neuropathologic assessment is performed following autopsy in most cases.
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Biochemical Society Transactions, 2001
Transmissible spongiform encephalopathies are diseases of animals and humans that are also termed prion diseases. These diseases are linked together because a normal brain glycoprotein termed the prion protein is converted to a readily detectable protease-resistant isoform.
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Transmissible spongiform encephalopathies are diseases of animals and humans that are also termed prion diseases. These diseases are linked together because a normal brain glycoprotein termed the prion protein is converted to a readily detectable protease-resistant isoform.
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Prion Protein Disease and Neuropathology of Prion Disease
Neuroimaging Clinics of North America, 2008Human prion diseases, in common with other neurodegenerative diseases, may be sporadic or inherited and are characterized by the accumulation of cellular proteins accompanied by neuronal death and synaptic loss. Prion diseases are, however, unique in being transmissible.
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2014
Prions are generally regarded as the most reliable markers of so-called prion diseases. With the advent of the protein-only concept of the transmission of prion diseases, which is predicated on the idea that prions are the infectious agents causing prion disease, and with the 1997 Nobel Prize for Medicine awarded for the prion protein concept, prions ...
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Prions are generally regarded as the most reliable markers of so-called prion diseases. With the advent of the protein-only concept of the transmission of prion diseases, which is predicated on the idea that prions are the infectious agents causing prion disease, and with the 1997 Nobel Prize for Medicine awarded for the prion protein concept, prions ...
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RT-QuIC Assays for Prion Disease Detection and Diagnostics.
Methods in molecular biology, 2017C. Orrú +9 more
semanticscholar +1 more source
Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 1997
Currently known transmissive spongiform encephalopathies in humans and animals are presented. Caused by prions, they are known as "prion disease". The results of extensive investigations of prions are described, as well as the theories about their nature.
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Currently known transmissive spongiform encephalopathies in humans and animals are presented. Caused by prions, they are known as "prion disease". The results of extensive investigations of prions are described, as well as the theories about their nature.
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A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis
Nature, 2020António Daniel Barbosa +2 more
exaly
Pathogenesis of prion diseases: current status and future outlook
Nature Reviews Microbiology, 2006Adriano Aguzzi
exaly
Insights into prion strains and neurotoxicity
Nature Reviews Molecular Cell Biology, 2007Adriano Aguzzi, Magdalini Polymenidou
exaly