Results 191 to 200 of about 5,604,422 (355)

Dopaminergic neurodegeneration in Gerstmann–Sträussler–Scheinker (P102L) disease: insights from imaging and pathological examination

Frontiers in Neurology
Gerstmann–Sträussler–Scheinker (GSS) disease is an inherited prion disease characterized by dementia, cerebellar ataxia, and painful sensory disturbances.
Ken-Ichi Irie, Ken-Ichi Irie, Hiroyuki Honda, Takahisa Tateishi, Shinichiro Mori, Shinichiro Mori, Akifumi Yamamoto, Makoto Morimitsu, Kikuchi Shinsuke, Taiga Moritaka, Seiji Kurata, Hiroyuki Kumazoe, Masahiro Shijo, Masahiro Shijo, Naokazu Sasagasako, Takayuki Taniwaki   +15 more
doaj   +1 more source

Purified prion proteins and scrapie infectivity copartition into liposomes.

, 1987
Ruth Gabizon, Michael P. McKinley, Stanley B. Prusiner   +2 more
openalex   +1 more source

Glycosylation differences between the normal and pathogenic prion protein isoforms [PDF]

, 1999
Pauline M. Rudd, Tama Endo, Cristina Colominas, Darlene Groth, Susan F. Wheeler, David J. Harvey, Mark R. Wormald, Hana Serban, Stanley B. Prusiner, Akira Kobata, Raymond A. Dwek   +10 more
openalex   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

Nature, 2016
A. Küffer, A. Lakkaraju, A. Mogha, Sarah C Petersen, Kristina Airich, C. Doucerain, Rajlakshmi Marpakwar, Pamela Bakirci, Assunta Senatore, Arnaud Monnard, C. Schiavi, M. Nuvolone, Bianka L. Grosshans, S. Hornemann, F. Bassilana, Kelly R. Monk, A. Aguzzi   +16 more
semanticscholar   +1 more source

Studying the Role of Myenteric Amyloidosis in Gastrointestinal Dysmotility and Enteric Neural Dysfunction Using APP/PS1 Mice—Is It an Adequate Animal Model?

Neurogastroenterology &Motility, EarlyView.
Amyloidosis in the central and enteric nervous system contributes to cognitive deficits and gastrointestinal dysmotility—the constipation in Alzheimer's disease (AD). APP/PS1 mice, a transgenic mouse model of amyloidosis, recapitulated the amyloidosis in the central nervous system; they were unsustainable in recapitulating the amyloidosis in the ...
Roxanne Fernandes, Marlene Masino, Emma Flood, Theresa A. Lansdell, Nikitha Srikrishna, Ryan Mui, Anne M. Dorrance, James J. Galligan, Hui Xu   +8 more
wiley   +1 more source

The role of VND transcription factors in xylem vessel development and secondary wall formation

New Phytologist, EarlyView.
Summary Transitioning from aquatic to terrestrial life required specialized vascular tissues, with xylem enabling water transport and structural support. Vascular‐related NAC (NAM, ATAF1/2, CUC2) domain (VND) transcription factors regulate xylem development by orchestrating secondary cell wall biosynthesis and programmed cell death.
Ulrike Lehmann, René Schneider
wiley   +1 more source

Specific Inhibition of in Vitro Formation of Protease-resistant Prion Protein by Synthetic Peptides [PDF]

, 1998
Joëlle Chabry, Byron Caughey, Bruce Chesebro   +2 more
openalex   +1 more source

Functional, pathogenic, and pharmacological roles of protein folding intermediates

Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 8, Page 1299-1307, August 2025.
Abstract Protein expression and function in eukaryotic cells are tightly harmonized processes modulated by the combination of different layers of regulation, including transcription, processing, stability, and translation of messenger RNA, as well as assembly, maturation, sorting, recycling, and degradation of polypeptides.
Emiliano Biasini, Pietro Faccioli
wiley   +1 more source

Prion and Prion-like Proteins

YAKUGAKU ZASSHI, 2019
Masato Hosokawa, Kazunori Sano
openaire   +3 more sources