Results 181 to 190 of about 56,657 (298)

Die Rolle von PrPC in der neuronalen Differenzierung und die Ausbreitung der infektiösen Isoform PrPSc durch Mikrovesikel

, 2008
Prion diseases or transmissible spongiform encephalopathies (TSEs) are rare neurological disorders that may be of genetic or infectious origin, but most frequently occur sporadically in humans. Their outcome is invariably fatal.
Barenco Montrasio, Maria Grazia
core  

Novel polymorphisms and functional characterization of the prion protein gene in sparrows (<i>Passer montanus</i>). [PDF]

Front Vet Sci
Truong CG, Choi DI, Jeong BH.
europepmc   +1 more source

Authorship and citation trends in dementia research: A path to equitable career development for scientists

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Women are increasingly entering the dementia research workforce, but they frequently fail to attain senior leadership positions in academia. Discrepancies in academic research outputs were investigated to guide equity‐focused policy recommendations.
Jayalakshmi Viswanathan, Diana Karamacoska, Lokendra S. Thakur, Mouna Sawan, Angela Gomez‐Arboledas, Ines Moreno‐Gonzalez, C. Elizabeth Shaaban, Sadaf A. Milani, Giedre Milinkeviciute, Samantha M. Loi, Anika Wuestefeld, Sindhuja T. Govindarajan, Audrey Low, Giovanna Carello‐Collar, Hom L. Shreshta, Sunnie Kenowsky, Claudia K. Suemoto, Michelle M. Mielke, Shana D. Stites   +18 more
wiley   +1 more source

Early onset Alzheimer's disease with V180I variant of prion protein gene and a family history of dementia: a case report. [PDF]

BMC Neurol
Hamaguchi T, Hamano T, Senoh T, Kawasaki Y, Uehara T, Satoh K, Hara N, Miyashita A, Ikeuchi T, Kitamoto T, Asahina M.   +10 more
europepmc   +1 more source

Structural and cellular properties of human prion protein oligomers. [PDF]

Commun Biol
Emendato A, Divisato G, Giannino E, Mansueto S, Zizolfi MC, Peltrini R, Parisi S, De Simone A.   +7 more
europepmc   +1 more source

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, Volume 73, Issue 3, Page 1115-1124, June 2026.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease.

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, MacKay, A, Thompson, AG, Porter, MC, Rudge, P, Collinge, J, Lowe, J, Mead, S, Uphill, J, Lukic, A   +9 more
core  

Genome-wide screens identify core regulators of cell surface prion protein expression. [PDF]

Sci Rep
Beauchemin KS, Supattapone S.
europepmc   +1 more source

5‐Hydroxytryptamine Distribution Alteration in Both Neuron and Synapse of Tg(SOD1*G93A)1gur Mice: A Potential Intervention Candidate Strategy for Amyotrophic Lateral Sclerosis

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This study reveals that 5‐hydroxytryptamine (5‐HT) synapses in the spinal cord and 5‐HT neurons in the brainstem of the SOD1‐G93A amyotrophic lateral sclerosis (ALS) mouse model are significantly altered, showing a decrease in pre‐symptomatic stages but a marked increase as the disease progresses.
Lijun Zhou, Menghua Li, Qi Dai, Xiwang Liu, Cheng Li, Huifeng Jiao, Haili Pan, Renshi Xu   +7 more
wiley   +1 more source

First report of novel single-nucleotide polymorphisms and genetic characteristics in the open reading frame of the prion protein gene (<i>PRNP</i>) in bats. [PDF]

Front Vet Sci
Tran DP, Choi DI, Na EJ, Oem JK, Jeong BH.   +4 more
europepmc   +1 more source