Results 171 to 180 of about 97,377 (307)
Protecting neurons from misfolded prion proteins [PDF]
, 2015 Monica Harrington
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Brain Pathology, Volume 36, Issue 3, May 2026.The study analyzed the seeding activity of misfolded tau protein in Alzheimer's disease and rapidly progressive Alzheimer's disease patients and provides evidence for the existence of different tau assemblies supported by differences in cellular toxicity and morphology of thioflavin T‐positive real‐time quaking‐induced conversion products.
Matthias Schmitz +13 more
wiley +1 more source
The cellular form of the prion protein is involved in controlling cell cycle dynamics, self‐renewal, and the fate of human embryonic stem cell differentiation [PDF]
, 2012 Young Jin Lee, Ilia V. Baskakov
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Brain Pathology, Volume 36, Issue 3, May 2026.The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown +7 more
wiley +1 more source
Structural and functional studies of monomeric and aggregated amyloidogenic forms of prion proteins
, 2002 Thorsten Lührs
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NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features. [PDF]
, 2010 Giachin, G +3 more
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In Vivo Comparison of Chronic Wasting Disease Infectivity from Deer with Variation at Prion Protein Residue 96 [PDF]
, 2011 Brent Race +4 more
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Mapping the functional domain of the prion protein [PDF]
, 2003 Taian Cui +6 more
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