Results 211 to 220 of about 56,806 (329)

Structural and Computational Study of the GroEL - Prion Protein complex

, 2021
А. А. Мамчур, Andrei V. Moiseenko, Irina S. Panina, Igor A. Yaroshevich, Sofia S. Kudryavtseva, Evgeny Pichkur, Olga S. Sokolova, Vladimir I. Muronetz, T.B. Stanishneva-Konovalova   +8 more
openalex   +2 more sources

Peripheral Signatures of Multidimensional Pathology in Symptomatic and Asymptomatic Creutzfeldt–Jakob Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Plasma biomarkers in CJD reveal multisystem involvement, with neuronal injury markers showing strong discriminative performance and vascular proteins indicating blood–brain barrier dysfunction. In asymptomatic PRNP mutation carriers, biomarker changes are minimal and emerge mainly near disease onset ABSTRACT Background Plasma markers of neuronal injury
Zhong‐Yun Chen, Min Chu, Yi‐Hao Wang, Rui Liu, Jing Zhang, Ai‐ling Yue, Hua Lu, Qian‐qian He, Jia‐hui Hou, Yu‐fei Chen, Hong Ye, Li‐Yong Wu   +11 more
wiley   +1 more source

Enhanced lysosomal activity prevents infection with PrP^Sc and the seeding activity of α-synuclein & tau prions. [PDF]

J Biol Chem
Mercer RCC, Le NTT, Mirza-Romero NA, Orbe IC, Flaherty E, DeFranco JP, Lavigna G, Gatdula JRP, Fraser DG, Sundaravadivelu A, Vultaggio JS, Beeler AB, Chiesa R, Telling GC, Harris DA.   +14 more
europepmc   +1 more source

Structural and functional studies of monomeric and aggregated amyloidogenic forms of prion proteins

, 2002
Thorsten Lührs
openalex   +1 more source

Evaluation of immunohistochemical detection of prion protein in rectoanal mucosa–associated lymphoid tissue for diagnosis of scrapie in sheep [PDF]

, 2009
Michelle M. Dennis, Bruce V. Thomsen, Katherine L. Marshall, S M Hall, Bruce A. Wagner, Μ. D. Salman, Dianne K. Norden, Charles Gaiser, Diane L. Sutton   +8 more
openalex   +1 more source

Oligodendroglial Densities and Myelin Structure Are Altered in TDP‐43 Related Amyotrophic Lateral Sclerosis

Glia, Volume 74, Issue 1, January 2026.
TDP‐43Q331K mice exhibit altered proliferative dynamics in oligodendrocytes and their precursors. Oligodendroglial cell death is evident in TDP‐43Q331K mice. TDP‐43Q331K mice display altered myelin reflectance and pathology in the spinal cord. ABSTRACT Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the ...
Katherine N. Lewis, Georgina A. Craig, Joel Mason, Doris Tomas, Brittany Cuic, Adam K. Walker, David G. Gonsalvez, Bradley J. Turner, Samantha K. Barton   +8 more
wiley   +1 more source

Collaborative strategies for wildlife health: case studies from the Canadian North

The Journal of Wildlife Management, Volume 90, Issue 1, January 2026.
The integration of Indigenous perspectives with a One Health approach enables culturally relevant and sustainable zoonotic disease management and surveillance, as demonstrated through 4 case studies that highlight how empowering communities and facilitating inclusive, respectful, and collaborative governance across diverse sectors and knowledge systems
Cody J. Malone, Douglas A. Clark, N. Jane Harms, Naima Jutha, Geraldine‐G. Gouin, Malik Awan, Lisa‐Marie Leclerc, Gabriel Antwi‐Boasiako, Emily J. Jenkins   +8 more
wiley   +1 more source

Locus coeruleus alterations in dementia with Lewy bodies: A systematic review

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION The locus coeruleus (LC) is a small nucleus located deep within the brainstem, serving as the brain's main source of noradrenergic neurons. Through its extensive projections, it plays a critical role in regulating cognitive processes and arousal.
Anaëlle Bain, Charlotte Tomeo, Claire André, Antoine Garnier‐Crussard, Robin de Flores, Sophie Dautricourt   +5 more
wiley   +1 more source

The Relative Importance of Floodplain Storage and Flow Path Dispersion on Flood Attenuation in Mountain Streams

Water Resources Research, Volume 62, Issue 1, January 2026.
Abstract Intensifying flooding throughout the western United States threatens human infrastructure, human life, and ecological integrity. Flash floods are particularly dangerous because they rise quickly and often unexpectedly. Floodplains that are hydrologically connected to river channels can act as buffers to attenuate peak flows and slow flood ...
Nicholas Christensen, Ryan R. Morrison
wiley   +1 more source

Infecting human brain organoids with FFI or sCJD preserves prion traits regardless of host genotype. [PDF]

NPJ Dement
Groveman BR, Foliaki ST, Williams K, Orrù CD, Race B, Zanusso G, Haigh CL.   +6 more
europepmc   +1 more source