Results 121 to 130 of about 8,574 (264)

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias, Sedef Kollarik, Michelle Siegel, Christian R. Baumann, Carlos G. Moreira, Daniela Noain   +5 more
wiley   +1 more source

Tick‐borne diseases in subtropical dairy farming: The role of calf rearing strategies in antibody and antigen prevalence Enfermedades Transmitidas por Garrapatas en la Ganadería Lechera subtropical: El Papel de las Estrategias de Crianza de Terneros en la Prevalencia de Anticuerpos y Antígenos

Medical and Veterinary Entomology, EarlyView.
Tropical farmers try to adapt calf‐rearing systems to temperate dairy industry standards. Calves in tick‐infested areas develop stronger immunity to TBD under controlled exposure to ticks. Early tick exposure promotes sustainable management, balancing tick infestation and developing TBD immunity.
Daniela Balseca, Valeria Paucar‐Quishpe, Richar Rodríguez‐Hidalgo, Ximena Pérez‐Otáñez, Darío Cepeda‐Bastidas, Cecilia Pérez‐Escalante, María‐Augusta Chávez‐Larrea, Sandra Enríquez, Jorge Grijalva, Sophie O. Vanwambeke, Claude Saegerman, Lenin Ron‐Garrido   +11 more
wiley   +1 more source

Long‐term stability of horizontal bone augmentation at implant sites

Periodontology 2000, EarlyView.
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu, Hui Jia Sophia Choo, Ding‐Sen Ong, Henry Kwek   +3 more
wiley   +1 more source

Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6

Neurobiology of Disease
Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is thought to occur when the cellular prion protein (PrPC) spontaneously misfolds and assembles into prion fibrils, culminating in fatal neurodegeneration.
Emma Jones, Elizabeth Hill, Jacqueline Linehan, Tamsin Nazari, Adam Caulder, Gemma F. Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin Sandberg, Emmanuelle Viré, Thomas J. Cunningham, Emmanuel A. Asante, Sebastian Brandner, John Collinge, Simon Mead   +18 more
doaj   +1 more source

How does a national blood operator detect early infectious disease signals affecting blood and cellular therapy product safety and sufficiency?

Transfusion, EarlyView.
Abstract Background Public access to up‐to‐date information on infectious diseases and outbreaks has grown rapidly with the advent of artificial intelligence platforms. While this information can improve patient care and support research, the sheer volume of available data coupled with the challenge of identifying misinformation and disinformation can ...
Leisa Bruneau, Carmen L. Charlton, Sandra Ramirez‐Arcos, Dilini Kumaran, David Allan, Olivia Norman, Matthew Seftel, Evan M. Bloch, Chantale Pambrun, Sheila F. O'Brien, Cynthia Cranney, Steven J. Drews   +11 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Manganese Could Indirectly Promote Generation and Propagation of the Yeast Prion [URE3] and Increase Molecular Chaperones Expression in Budding Yeast

Applied Sciences
Prion diseases are caused by self-propagating and transmissible alternative conformations of certain proteins, which induce neurotoxicity and lead to transmissible spongiform encephalopathy (TSE) in mammalian.
Hui-Yong Lian, Yu-Hang Zhang, Kang-Wei Lin, Tingting Zhu   +3 more
doaj   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Proteins as markers of TSE infection in sheep blood

, 2008
Transmissible spongiform encephalopathies (TSEs) are a group of fatal infectious neurodegenerative diseases affecting both humans and agricultural animals. TSE transmission via blood transfusion has been demonstrated experimentally in rodent, primate and
Martin, Joanne
core   +1 more source

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

Annals of Neurology, Volume 100, Issue 4, Page 737-750, October 2026.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber, Ricardo Hernández Arriaza, Dylan Reil, Manon Muntaner, Junyoung Park, Benjamin Grenier‐Boley, Marc Hulsman, Philippe Amouyel, Céline Bellenguez, Camille Charbonnier, Jean‐François Deleuze, Orio Dols‐Icardo, John Hardy, Henne Holstege, Gaël Nicolas, Simon Mead, Michael Wagner, Alfredo Ramirez, Rebecca Sims, John van Swieten, Julie Willams, Jean‐Charles Lambert, Chaitan Khosla, Yann Le Guen, Michael D Greicius   +24 more
wiley   +1 more source