Results 191 to 200 of about 8,300 (285)

Endoscopic Ultrasonography‐Guided Gastroenterostomy Is More Cost Effective Than Surgical Gastrojejunostomy: A Health‐Economic Evaluation Alongside a Randomized Trial

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background There is a paucity of data on the cost‐utility of endoscopic ultrasonography‐guided gastroenterostomy (EUS‐GE) compared with surgical gastrojejunostomy (SGJ) as palliative treatment of malignant gastric outlet obstruction. Methods In the ENDURO trial, 98 patients with malignant gastric outlet obstruction from 12 Dutch hospitals were
Yorick L. van de Pavert, Kirsten Opmeer, Marc G. Besselink, Rina Bijlsma, Dieke C. Booij, Jurjen J. Boonstra, Judith Boot, Marco J. Bruno, Olivier R. Busch, Freek Daams, Wouter J. M. Derksen, Paul Fockens, Janine B. Kastelijn, Bas Groot Koerkamp, Jeroen Hagendoorn, Jeanin E. van Hooft, Akin Inderson, Willem J. Lammers, Daan J. Lips, J. Sven D. Mieog, I. Quintus Molenaar, Alexander A. F. A. Veenhof, Niels G. Venneman, Robert C. Verdonk, Rogier P. Voermans, Roy L. J. van Wanrooij, Paco M. J. Welsing, Thomas R. de Wijkerslooth, Hjalmar C. van Santvoort, Leon M. G. Moons, Miriam P. van der Meulen, Frank P. Vleggaar, for the Dutch Pancreatic Cancer Group   +32 more
wiley   +1 more source

Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains. [PDF]

Proc Natl Acad Sci U S A
DeFranco JP, Bian J, Kim S, Atkinson ZN, Crowell J, Kang HE, Bodrogi HO, Christiansen JR, Díaz-Domínguez CM, Telling GC.   +9 more
europepmc   +1 more source

Mimicking the Ocean: Critical Challenges in Scaffold Design and Tissue Texturization for Cell‐Cultured Seafood

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Cellular aquaculture offers a sustainable solution to global seafood demand, yet the production of high‐value, whole‐cut fillets is hindered by the “texture gap,” the inability to replicate the complex, anisotropic architecture of native fish muscle and its collagenous myosepta.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Involvement of the spleen in the anti-prion activity of hydroxypropyl methylcellulose in mice. [PDF]

Sci Rep
Teruya K, Oguma A, Nishizawa K, Doh-Ura K.   +3 more
europepmc   +1 more source

RORA Targeting PRNP Modulates Age‐Related Cataract via Activation Oxidative Injury‐Induced Cellular Senescence and Apoptosis of Lens Epithelial Cells

Aging Cell, Volume 25, Issue 6, June 2026.
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou, Wanqian Li, Jiaojiao Zhang, Chao Cen, Wanqiu Zheng, Ruonan Li, Hong Cheng, Liang Liang, Juan Kang, Wenjuan Wan, Ke Hu, Shijie Zheng   +11 more
wiley   +1 more source

Enhanced lysosomal activity prevents infection with PrP^Sc and the seeding activity of α-synuclein & tau prions. [PDF]

J Biol Chem
Mercer RCC, Le NTT, Mirza-Romero NA, Orbe IC, Flaherty E, DeFranco JP, Lavigna G, Gatdula JRP, Fraser DG, Sundaravadivelu A, Vultaggio JS, Beeler AB, Chiesa R, Telling GC, Harris DA.   +14 more
europepmc   +1 more source

Active Chlorine Antiseptics in Wound Care: Recent Advances and Perspectives for Military Medicine

APMIS, Volume 134, Issue 6, June 2026.
ABSTRACT The spread of multidrug‐resistant microorganisms remains a major global challenge that continues to worsen. Modern military conflicts intensify this problem by forcing healthcare systems to manage large numbers of patients with complex, heavily contaminated injuries in resource‐limited settings.
Bohdan Murashevych, Dmytro Stepanskyi, William M. Wuest, Tim Holm Jakobsen   +3 more
wiley   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, Volume 208, Issue 6, Page 1980-1992, June 2026.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

A model-based prion vaccine protects a transgenic mouse line carrying a Gerstmann-Sträussler-Scheinker disease mutation. [PDF]

Acta Neuropathol
Fang A, Tang X, Fleming M, Tancowny B, Wang X, Wang Y, Daude N, Dorosh L, Fleck SC, Rathod V, Coustou V, Cervantes SA, Velásquez CD, Westaway D, Aiken J, McKenzie D, Telling G, Stepanova M, Saupe SJ, Siemer AB, Wille H.   +20 more
europepmc   +1 more source

Antibodies directed against the 37 kDa/67 kDa laminin receptor as therapeutic tools for the treatment of prion diseases and cancer [PDF]

, 2008
Zuber, Chantal
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