Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs. [PDF]
Le NTT +9 more
europepmc +1 more source
Bovine Spongiform Encephalopathy: An Integrated Review of Prion Mechanisms, Neuroanatomy, and Control. [PDF]
Marzola GP +6 more
europepmc +1 more source
Beyond prion-like spreading in neurodegenerative disease. [PDF]
Meisl G, Rowe JB, Klenerman D.
europepmc +1 more source
Presymptomatic pharmacological inhibition of mGluR5 improves survival in a mouse model of prion diseases. [PDF]
Wang Y +13 more
europepmc +1 more source
3D atomic structure reveals evolution of prions in templated amplification in vitro
Bieschke J +11 more
europepmc +1 more source
Scalable assay to identify inhibitors of prion-like propagation of protein misfolding as potential therapeutics for neurodegeneration. [PDF]
Narayan A, Neupane K, Woodside MT.
europepmc +1 more source
Infecting human brain organoids with FFI or sCJD preserves prion traits regardless of host genotype. [PDF]
Groveman BR +6 more
europepmc +1 more source
Prion Diseases-When Proteins Turn Lethal: Creutzfeldt-Jakob Disease (CJD) and the Quest for Classification, Diagnosis, Therapeutic Approaches, and Emerging Research. [PDF]
Ramesh TS +3 more
europepmc +1 more source

