Results 221 to 230 of about 16,731 (246)

Alzheimer’s and Parkinson’s diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein

Science, 2015
Converging paradigms in neurodegeneration Parkinson's disease and Alzheimer's disease are progressive neurodegenerative diseases with increasing prevalence in our aging populations. Recent evidence suggests that some of the molecular mechanisms involved in the pathology of these diseases have similarities to those observed in infectious prion
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Mechanism of Neurotoxicity of Prion and Alzheimer's Disease-Related Proteins: Molecular Insights from Bioinformatically Identified ω-Conotoxin-Like Pharmacophores

Critical Reviews in Eukaryotic Gene Expression, 2013
Prion diseases are fatal neurodegenerative disorders caused by altered forms of the prion protein (PrPC). It was reported that dysregulation of cellular Ca2+ homeostasis is recurrent in these diseases and that scrapie-infected cells exhibit Ca2+ perturbation via specific impairment of N-type calcium channels.
openaire   +2 more sources

Prion‐related diseases and Creutzfeldt–Jakob disease (subacute spongiform encephalopathy)

European Journal of Neurology, 1996
F. Boiler, C. Duyckaerts, O. Paulson, S. Vorstrup, P. Soelberg Sørensen   +4 more
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Future counselling of donors and recipients of blood products concerning prion‐related diseases

Vox Sanguinis, 2003
Reesink, H. W., Engelfriet, C. P., Muylle, L., Wendel, S., Dickmeiss, E., Krusius, T., Mäki, T., Lin, C. K., O'Riordan, J., Prati, D., Rebulla, P., Shirato, T., Nakajima, K., Dupuis, H. M., Flanagan, P., Carasa, M. A. V., Gallastegui, R. A., Turek, P., Hewitt, P., Bernat, J. L., Bianco, C., Dodd, R. Y., Klein, H. G.   +22 more
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Prions and their lethal journey to the brain

Nature Reviews Microbiology, 2006
Neil A Mabbott
exaly  

Prions of fungi: inherited structures and biological roles

Nature Reviews Microbiology, 2007
Reed B Wickner, Herman Edskes, Frank Shewmaker   +2 more
exaly  

NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein.

Science (New York, N.Y.), 2015
The pathological assembly of Aβ, tau, and α-synuclein is at the heart of Alzheimer's and Parkinson's diseases. Extracellular deposits of Aβ and intraneuronal tau inclusions define Alzheimer's disease, whereas intracellular inclusions of α-synuclein make up the Lewy pathology of Parkinson's disease.
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Prions, prionoids and protein misfolding disorders

Nature Reviews Genetics, 2018
Claudia Scheckel, Adriano Aguzzi
exaly  

Women's Occupations, Smoking, and Cancer and Other Diseases

Ca-A Cancer Journal for Clinicians, 1981
Steven D Stellman
exaly  

Prions: health scare and biological challenge

Nature Reviews Molecular Cell Biology, 2001
Adriano Aguzzi, Fabio Montrasio, Pascal S Kaeser   +2 more
exaly