Results 81 to 90 of about 218,901 (254)

Quantum Smoluchowski equation: A systematic study

open access: yes, 2010
The strong friction regime at low temperatures is analyzed systematically starting from the formally exact path integral expression for the reduced dynamics.
A. G. Redfield   +9 more
core   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Comment on "Effects of Thickness on the Spin Susceptibility of the Two Dimensional Electron Gas"

open access: yes, 2006
A comment on a recent paper (PRL {\bf 94}, 226405 (2005)) by S. De Palo, M. Botti, S.
Lazaridou, M. S.   +4 more
core   +2 more sources

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang   +12 more
wiley   +1 more source

Relacje polsko-austriackie u schyłku zimnej wojny w świetle polskich źródeł dyplomatycznych

open access: yesPrzegląd Nauk Historycznych
Przyjęte metody badań historycznych miały za zadanie odpowiedzieć na pytanie, czy państwa wschodnie sąsiadujące z Austrią, ograniczone swym systemem gospodarczym i politycznym, mogły liczyć na pomoc w zakresie inicjowania reform politycznych ...
Agnieszka Kisztelińska-Węgrzyńska
doaj   +1 more source

Characterization of Chicken Prolactin Regulatory Element Binding Protein and its Expression in the Anterior Pituitary Gland during Embryogenesis and Different Reproductive Stages

open access: yesThe Journal of Poultry Science, 2015
The PRL regulatory element binding protein (PREB) is a transcription factor that specifically binds to a Pit-1 binding element in the PRL promoter to regulate PRL gene expression in mammals.
Gen Hiyama   +4 more
doaj   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

open access: yesAdvanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang   +11 more
wiley   +1 more source

Effects of Vasoactive Intestinal Polypeptide and Forskolin on mRNA Expression of Prolactin and Prolactin Regulatory Element-Binding Protein in the Anterior Pituitary Gland of Chicken Embryo and Laying Hens

open access: yesThe Journal of Poultry Science, 2016
Vasoactive intestinal peptide (VIP) treatment induced mRNA expression of Prolactin (PRL) in the chicken anterior pituitary gland. VIP responsive element (VRE) of the PRL promoter was identified in the various bird species. However, transcription factor,
Norio Kansaku   +7 more
doaj   +1 more source

Pattern formation on the surface of cationic-anionic cylindrical aggregates

open access: yes, 2005
Charged pattern formation on the surfaces of self--assembled cylindrical micelles formed from oppositely charged heterogeneous molecules such as cationic and anionic peptide amphiphiles is investigated.
A. Ben-Naim   +7 more
core   +1 more source

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