Results 101 to 110 of about 3,653 (217)
Journal of Research in Medical Sciences, 2011 Background: The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a nuclear hormone receptor. It is predominantly expressed in adipose tissue and as a receptor for thiazolidinediones, it has drawn attentions towards itself as a key molecule to ...
Fatemeh Namvaran +2 more
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The Egyptian Journal of Internal Medicine, 2013 Background Diabetic nephropathy is one of the debilitating complications of type 2 diabetes and the leading cause for end-stage renal disease requiring renal replacement therapy.
Asmaa I. Ahmed +3 more
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Animal Models of GWAS-Identified Type 2 Diabetes Genes [PDF]
, 2013 More than 65 loci, encoding up to 500 different genes, have been implicated by genome-wide association studies (GWAS) as conferring an increased risk of developing type 2 diabetes (T2D).
Bellomo, EA +4 more
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Enhanced role of PPARg with the Pro12Ala polymorphism
, 2013 Obesity and type 2 diabetes mellitus (T2D) are two major public health problems that have motivated the scientific community to investigate the high contribution of genetic factors to these disorders. The peroxisome proliferator activated by gamma 2 (PPARg2) plays an important role in the lipid metabolism.
Fernandes, Rúben +3 more
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Pro12Ala and His447His polymorphisms of PPAR-γ are associated with polycystic ovary syndrome
Reproductive BioMedicine Online, 2009 Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects 4-12% of women of reproductive age, and is specified when two of the three following criteria are present: hyperandrogenism, oligomenorrhoea and polycystic ovary morphology by ultrasonography. PCOS is characterized by infertility, obesity and hyperinsulinaemia.
Bon-Hee, Gu, Kwang-Hyun, Baek
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Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]
, 2020 "Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
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THE ASSOCIATION OF GENE POLYMORPHISMS WITH ATHLETE STATUS IN UKRAINIANS [PDF]
, 2013 Athletic performance is a polygenic trait influenced by both environmental and genetic factors. Objective: to investigate individually and in combination the association of common gene polymorphisms with athlete status in Ukrainians.
Ildus I. Ahmetov +3 more
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Genetics and Molecular Research, 2015 We investigated whether Pro12Ala (C→G) and His447His (C→T) polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARγ) gene are associated with susceptibility to Alzheimer's disease (AD). We conducted a meta-analysis of the associations between the PPARγ Pro12Ala and His447His polymorphisms and AD in subjects.
Y H, Lee, G G, Song
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Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease
PPAR Research, 2009 Single nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptor γ (PPARG) gene have been associated with cardiovascular risk factors, particularly obesity and diabetes. We assessed the relationship between 4 PPARG SNPs (C-681G, C-
Jean Dallongeville +13 more
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Patologìâ, 2016 Aim – to study the impact of polymorphic marker rs1801282 of gene PPARG on the formation of oxidative stress in terms of LPO and AOS in patients with type 2 diabetes depending on the duration of the disease. Materials and methods.
V. Y. Mokrii, S. V. Ziablytsev
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