Results 81 to 90 of about 1,172 (173)

Genotyping of peroxisome proliferator-activated receptor gamma (PPAR-γ) polymorphism (Pro12Ala) in Iranian population

Journal of Research in Medical Sciences, 2011
Background: The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a nuclear hormone receptor. It is predominantly expressed in adipose tissue and as a receptor for thiazolidinediones, it has drawn attentions towards itself as a key molecule to ...
Fatemeh Namvaran, Parvaneh Rahimi-Moghaddam, Negar Azarpira   +2 more
doaj  

The association between diabetic nephropathy and polymorphisms in PPARγ Pro12Ala and CCR5δ 32 genes in type 2 diabetes

The Egyptian Journal of Internal Medicine, 2013
Background Diabetic nephropathy is one of the debilitating complications of type 2 diabetes and the leading cause for end-stage renal disease requiring renal replacement therapy.
Asmaa I. Ahmed, Noha A. Osman, Mohamed M. NasrAllah, Manal M. Kamal   +3 more
doaj   +1 more source

Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease

PPAR Research, 2009
Single nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptor γ (PPARG) gene have been associated with cardiovascular risk factors, particularly obesity and diabetes. We assessed the relationship between 4 PPARG SNPs (C-681G, C-
Jean Dallongeville, Carlos Iribarren, Jean Ferrières, Liisa Lyon, Alun Evans, Alan S. Go, Dominique Arveiler, Stephen P. Fortmann, Pierre Ducimetière, Mark A. Hlatky, Philippe Amouyel, Audrey Southwick, Thomas Quertermous, Aline Meirhaeghe   +13 more
doaj   +1 more source

Effect of Pro12Ala polymorphism of PPARG gene on lipid peroxidation and antioxidant defense in patients with type 2 diabetes depending on the duration of the disease

Patologìâ, 2016
Aim – to study the impact of polymorphic marker rs1801282 of gene PPARG on the formation of oxidative stress in terms of LPO and AOS in patients with type 2 diabetes depending on the duration of the disease. Materials and methods.
V. Y. Mokrii, S. V. Ziablytsev
doaj   +1 more source

The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

Nature Genetics, 2000
Genetic association studies are viewed as problematic and plagued by irreproducibility. Many associations have been reported for type 2 diabetes, but none have been confirmed in multiple samples and with comprehensive controls. We evaluated 16 published genetic associations to type 2 diabetes and related sub-phenotypes using a family-based design to ...
Altshuler, D, Hirschhorn, J, Klannemark, M, Lindgren, C, Vohl, M, Nemesh, J, Lane, C, Schaffner, S, Bolk, S, Brewer, C, Tuomi, T, Gaudet, D, Hudson, T, Daly, M, Groop, L, Lander, E   +15 more
openaire   +2 more sources

Correlation between PPARG Pro12Ala Polymorphism and Therapeutic Responses to Thiazolidinediones in Patients with Type 2 Diabetes: A Meta-Analysis. [PDF]

Pharmaceutics, 2023
Jang EJ, Lee DH, Im SS, Yee J, Gwak HS.
europepmc   +1 more source

The Role of Peroxisome Proliferator-Activated Receptors in Polycystic Ovary Syndrome. [PDF]

J Clin Med, 2023
Psilopatis I, Vrettou K, Nousiopoulou E, Palamaris K, Theocharis S.   +4 more
europepmc   +1 more source

Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers

Upsala Journal of Medical Sciences, 2017
Aim: To assess practical implications of genotype-based recall (GBR) studies, an increasingly popular approach for in-depth characterization of genotype–phenotype relationships.
Prasad G. Kamble, Stefan Gustafsson, Maria J. Pereira, Per Lundkvist, Naomi Cook, Lars Lind, Paul W. Franks, Tove Fall, Jan W. Eriksson, Erik Ingelsson   +9 more
doaj   +1 more source

Genetic polymorphism of Pro12Ala in type 2 diabetes mellitus: Role in inflammation linked to Insulin resistance. [PDF]

Bioinformation, 2023
Bonam VR, Srinivasan AR, DanielDevaprasad M, Kudikala RB.   +3 more
europepmc   +1 more source

Metabolic Biomarkers in Adults with Type 2 Diabetes: The Role of PPAR-γ2 and PPAR-β/δ Polymorphisms. [PDF]

Biomolecules, 2023
Reza-López SA, González-Gurrola S, Morales-Morales OO, Moreno-González JG, Rivas-Gómez AM, González-Rodríguez E, Moreno-Brito V, Licón-Trillo A, Leal-Berumen I.   +8 more
europepmc   +1 more source