Results 81 to 90 of about 3,653 (217)

Association Between Pro12Ala Polymorphism of Peroxisome ProliferatorActivated Receptor Gamma (PPARγ) and Components of Metabolic Syndrome

Endocrinology Research and Practice, 2010
Objective: Metabolic syndrome is a highly prevalent complex disorder characterized by abdominal obesity, insulin resistance, dyslipidemia and hypertension. It occurs as a result of the interaction between genetic susceptibility and environmental factors,
Tomris Erbaş
doaj   +2 more sources

Effects of the PPARG gene polymorphisms on markers of obesity and the metabolic syndrome in Bosnian subjects [PDF]

Journal of Medical Biochemistry, 2014
Background: Peroxisome proliferator-activated receptor gamma (PPARg) is a key transcription factor in adipogenesis, and also regulates a number of genes associated with lipid storage and insulin sensitivity.
Dujić Tanja, Bego Tamer, Mlinar Barbara, Semiz Sabina, Malenica Maja, Prnjavorac Besim, Ostanek Barbara, Marc Janja, Čaušević Adlija   +8 more
doaj  

Association of FTO and PPARG polymorphisms with obesity in Portuguese women [PDF]

, 2013
Purpose: We evaluated the association between risk of obesity in the Portuguese population and two obesity-related single-nucleotide gene polymorphisms: fat-mass and obesity-associated (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma (
Baptista, Pedro Viana, Brito, Miguel, Carlos, Fábio Ferreira, Doria, Gonçalo, Flores, Orfeu, Silva-Nunes, José, Veiga, Luísa   +6 more
core   +1 more source

THE VALUE OF POLYMORPHISM RRO12ALA GENE PPARG IN VIOLATION OF LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION IN PATIENTS WITH TYPE 2 DIABETES

Ukrainian Scientific Medical Youth Journal, 2016
Resume. The incidence of type 2 diabetes is increasing in Ukraine and worldwide. The severity of this disease is determined by the number of complications, which are based on lipid peroxidation (LPO).
V. Y. Mokrii, S. V. Ziablytsev, M. V. Cryshtal   +2 more
doaj   +1 more source

The Single Nucleotide Polymorphism PPARG2 Pro12Ala Affects Body Mass Index, Fat Mass, and Blood Pressure in Severely Obese Patients

Journal of Obesity, 2018
Background. The PPARG2 Pro12Ala (rs1801282) and IL6 -174G >C (rs1800795) have important function in body weight regulation and a potential role in obesity risk. We aimed to investigate the association between PPARG2 Pro12Ala and IL6 -174G >C variants and
Ana Paula dos Santos Rodrigues, Lorena Pereira Souza Rosa, Hugo Delleon da Silva, Elisângela de Paula Silveira-Lacerda, Erika Aparecida Silveira   +4 more
doaj   +1 more source

PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial

Nutrition & Metabolism, 2018
Background Previous intervention studies have reported the association of the PPARG2 Pro12Ala (rs1801282) and IL6 -174G > C (rs1800795) polymorphisms with weight loss; however, their results are inconsistent.
Ana Paula Santos Rodrigues, Lorena Pereira Souza Rosa, Erika Aparecida Silveira   +2 more
doaj   +1 more source

The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is associated with increased risk of coronary artery disease: a meta-analysis. [PDF]

PLoS ONE, 2012
BACKGROUND: Contradictory results have been reported regarding the association between Pro12Ala polymorphism of PPARγ2 and coronary artery disease (CAD). We sought to estimate the inconsistent results by performing a comprehensive meta-analysis. METHODS:
Zhijun Wu, Yuqing Lou, Wei Jin, Yan Liu, Lin Lu, Guoping Lu   +5 more
doaj   +1 more source

Pharmacogenetics in Type 2 Diabetes: Potential Implications for Clinical Practice [PDF]

, 2013
Pharmacogenetic research aims to study how genetic variation may influence drug efficacy and/or toxicity; pharmacogenomics expands this quest to the entire genome. Pharmacogenetic findings may help to uncover new drug targets, illuminate pathophysiology,
Florez, Jose Carlos, Huang, Chunmei
core   +1 more source

Subject Index

, 2020
Journal of Diabetes Investigation, Volume 11, Issue 6, Page 1686-1703, November 2020.
wiley   +1 more source

Study on distribution of Pro12Ala single nucleotide polymorphism of PPARγ2 gene in randomly sampled diabetic population from Guwahati city

Italian Journal of Medicine, 2014
Diabetes is one of the most fatal and vastly heritable metabolic disorders across the globe primarily due to the associated long-term effects including uncontrolled blood sugar levels, blindness, renal and cardiac problems.
Navaneeta Majumdar, Ananya Bhowmick, Purabi Sarkar, Rhituraj Doley, Indrajit Kalita, Subhash S. Medhi, Sofia Banu   +6 more
doaj   +1 more source