Results 71 to 80 of about 1,172 (173)

PPARgamma-Polymorphismus (Pro12Ala) [PDF]

, 2002
Es handelt sich um eine retrospektive klinische Studie, bei der wir den Einfluss der relativ häufig auftretenden Pro 12 Ala Mutation in PPARgamma auf das Körpergewichtund den Gewichtsverlauf nach gastric banding Operationen untersucht haben. Weiter untersuchten wir Parameter des Glukosestoffwechsels (Glukose, Insulin, C-Peptid).
openaire  

PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial

Nutrition & Metabolism, 2018
Background Previous intervention studies have reported the association of the PPARG2 Pro12Ala (rs1801282) and IL6 -174G > C (rs1800795) polymorphisms with weight loss; however, their results are inconsistent.
Ana Paula Santos Rodrigues, Lorena Pereira Souza Rosa, Erika Aparecida Silveira   +2 more
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Enhanced role of PPARg with the Pro12Ala polymorphism

, 2013
Obesity and type 2 diabetes mellitus (T2D) are two major public health problems that have motivated the scientific community to investigate the high contribution of genetic factors to these disorders. The peroxisome proliferator activated by gamma 2 (PPARg2) plays an important role in the lipid metabolism.
Fernandes, Rúben, Pereira, Ana Cláudia, Oliveira, Rosa, Prudêncio, Cristina   +3 more
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The Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor Gamma Gene Modifies the Association of Physical Activity and Body Mass Changes in Polish Women

PPAR Research, 2014
Peroxisome proliferator-activated receptor γ is a key regulator of adipogenesis, responsible for fatty acid storage and maintaining energy balance in the human body.
Aleksandra Zarebska, Zbigniew Jastrzebski, Pawel Cieszczyk, Agata Leonska-Duniec, Katarzyna Kotarska, Mariusz Kaczmarczyk, Marek Sawczuk, Agnieszka Maciejewska-Karlowska   +7 more
doaj   +1 more source

Study on distribution of Pro12Ala single nucleotide polymorphism of PPARγ2 gene in randomly sampled diabetic population from Guwahati city

Italian Journal of Medicine, 2014
Diabetes is one of the most fatal and vastly heritable metabolic disorders across the globe primarily due to the associated long-term effects including uncontrolled blood sugar levels, blindness, renal and cardiac problems.
Navaneeta Majumdar, Ananya Bhowmick, Purabi Sarkar, Rhituraj Doley, Indrajit Kalita, Subhash S. Medhi, Sofia Banu   +6 more
doaj   +1 more source

Analysis of associations of PPARGC1A and PPARG genes polymorphisms with metabolic syndrome in persons with vibration disease

Якутский медицинский журнал
The aim of this work was to study the relationship between Pro12Ala polymorphisms of the PPARG gene and Gly482Ser of the PPARGC1A gene with metabolic syndrome in individuals with VD.
L. B. Masnavieva, I. V. Kudaeva, O. A. Dyakovich, N. P. Chistova, O. V. Naumova   +4 more
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Correlation between PPAR Gene Polymorphisms and Primary Nephrotic Syndrome in Children

PPAR Research, 2013
Pediatric primary nephrotic syndrome (PNS) is a chronic disease promoted by metabolic and immune dysfunctions. Peroxisome proliferator-activated receptor (PPAR) polymorphisms have been associated with a variety of metabolic and kidney disorders.
Jiaping Jin, Guixia Ding, Huaying Bao, Ying Chen, Yuan Han, Fei Zhao, Songming Huang, Aihua Zhang   +7 more
doaj   +1 more source

Association of the Pro12Ala Polymorphism with the Metabolic Parameters in Women with Polycystic Ovary Syndrome

Open Access Macedonian Journal of Medical Sciences, 2017
AIM: To investigate the association of peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism with polycystic ovary syndrome (PCOS) and its effect on the metabolic parameters in PCOS women.METHODS: The study used PCR to identify the presence of the PPARG Pro12Ala polymorphism in 100 PCOS women and 120 age-matched healthy women ...
Zaki, Moushira, Hassan, Naglaa, El-Bassyouni, Hala T., Kamal, Sanaa, Basha, Walaa, Azmy, Osama, Amr, Khalda   +6 more
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Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patients with primary knee osteoarthritis

Annals of Saudi Medicine, 2011
Background and Objectives: Peroxisome proliferator-activated receptors (PPARs) play an important role in a number of cellular and metabolic functions. This study was carried out to determine the prevalence of a missense mutation (Pro12Ala) in the PPARG2 ...
Al-Jarallah Khaled, Shehab Diaa, Haider Mohammad   +2 more
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The Pro12Ala Polymorphism of PPAR-γ Gene Is Associated with Sepsis Disease Severity and Outcome in Chinese Han Population

PPAR Research, 2014
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a ligand-binding nuclear receptor, and its activation plays a prominent role in regulating the inflammatory response. Therefore, PPAR-γ has been suggested as a candidate gene for sepsis.
Guoda Ma, Haiyang Wang, Guixi Mo, Lili Cui, You Li, Yiming Shao, Xin Liu, Yuliu Xie, Jia Li, Jiawu Fu, Hua Tao, Bin Zhao, Liangqing Zhang, Keshen Li   +13 more
doaj   +1 more source