Results 71 to 80 of about 3,653 (217)

Assessment of association between the Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications

Zaporožskij Medicinskij Žurnal, 2019
Aim – to determine the association between Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications. Materials and methods. A total of 97 women with normal prepregnancy weight, singleton pregnancy, delivery at 37 weeks or more and
S. O. Ostafiichuk
doaj   +1 more source

Polymorphism of Pro12Ala in the peroxisome proliferator-activated receptor 2 gene in Iranian diabetic and obese subjects

, 2009
Background: Peroxisome proliferator-activated receptor 2 (PPAR2) is a nuclear receptor that regulates adipocyte differentiation, lipid metabolism, and insulin sensitivity.
Akrami, S.M., Amiri, P., Doosti, M., Golmohammadi, T., Heshmat, R., Mirzaei, H., Nakhjavani, M.   +6 more
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Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 gene on lipid profile and adipokines levels in obese subjects

Balkan Journal of Medical Genetics, 2017
Peroxisome proliferator-activated receptor γ (PPARγ) is a key regulator of metabolism, adipokines production and secretion. The aim of this study was to investigate the association between the PPARγ2 gene Pro12Ala polymorphism in obesity in terms of body
Becer E, Çırakoğlu A
doaj   +1 more source

Pharmacogenetics of oral antidiabetic drugs [PDF]

, 2013
Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register
Becker, Matthijs L., Pearson, Ewan R., Tkáč, Ivan   +2 more
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Der PPARγ-Pro12Ala-Polymorphismus und metabolisches Syndrom

, 2006
The burden of chronic diseases, e. g. coronary heart diseases and diabetes, is rapidly increasing worldwide. Coronary heart diseases and diabetes are connected with lifestyle and dietary patterns. However, the genetic background in the pathogenesis of these diseases is considered to be important too. Because of that complex interplay these diseases are
openaire   +2 more sources

PPARG2 Pro12Ala and TNFα -308G>A Polymorphisms Are Not Associated with Heart Failure Development in Patients with Ischemic Heart Disease after Coronary Artery Bypass Grafting

PPAR Research, 2019
TNFα and PPARγ are important modulators of metabolism, inflammation, and atherosclerosis. Coronary artery disease is the leading cause of heart failure (HF).
Izabela Wojtkowska, Tomasz A. Bonda, Andrzej Tysarowski, Katarzyna Seliga, Janusz A. Siedlecki, Maria M. Winnicka, Janina Stępińska   +6 more
doaj   +1 more source

Influence of the body mass and visceral adiposity on glucose metabolism in obese women with Pro12Pro genotype in PPARgamma2 gene. [PDF]

, 2016
Introduction: Glucose metabolism may be altered in obesity and genotype for PPAR 2 can influence this variable. Objective: To evaluate the influence of body mass (BM) and visceral adiposity (VA) in glucose metabolism in morbid obese women with Pro12Pro ...
D'ANDREA, C. L., KAIPPERT, V. C., LAGO, M. F. do, LOPES, M. C. O. dos S., NOGUEIRA, J., OLIVEIRA, E. M. M., ROSADO, E. L., UEHARA, S. K.   +7 more
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PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabolic syndrome

Cardiovascular Diabetology, 2011
Background Metabolic Syndrome (MetS) results from the combined effect of environmental and genetic factors. We investigated the possible association of peroxisome proliferator-activated receptor-γ2 (PPARγ2) Pro12Ala and Angiotensin Converting Enzyme (ACE)
Passaro Angela, Dalla Nora Edoardo, Marcello Caterina, Di Vece Francesca, Morieri Mario, Sanz Juana M, Bosi Cristina, Fellin Renato, Zuliani Giovanni   +8 more
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Investigação do polimorfismo pro12ala no gene do receptor ativado por proliferador de Peroxissomo-gama (PPARy) em pacientes com síndrome metabólica [PDF]

, 2014
Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2014.Texto parcialmente liberado pelo autor.
Rocha, Renato Marano
core  

Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction [PDF]

, 2009
Despite remarkable progress in diagnosis and understanding of risk factors, cardiovascular disease (CVD) remains still the leading cause of morbidity and mortality in the world\u27s developed countries.
Andreassi, Maria Grazia
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