Results 51 to 60 of about 3,653 (217)

The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline [PDF]

Alzheimer Disease & Associated Disorders, 2018
Previous reports suggest race/ethnic and sex heterogeneity in the association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma (PPARG) gene and cognitive decline. Tests of verbal memory, processing speed, and verbal fluency and a composite global Z-score were used to assess cognitive performance longitudinally ...
Nancy A, West, Jonathan V, Tingle, Jeannette, Simino, Elizabeth, Selvin, Jan, Bressler, Thomas H, Mosley   +5 more
openaire   +2 more sources

Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. [PDF]

, 2013
ObjectiveWe aimed to identify factors that are independently associated with the metabolic clearance rate of insulin (MCRI) and to examine the association of MCRI with incident type 2 diabetes in nondiabetic Hispanics and African Americans.Research ...
Anderson, Andrea M, Bergman, Richard N, Goodarzi, Mark O, Haffner, Steven M, Hanley, Anthony J, Lee, C Christine, Lorenzo, Carlos, Norris, Jill M, Rotter, Jerome I, Stefanovski, Darko, Wagenknecht, Lynne E   +10 more
core   +2 more sources

CHO intake alters obesity risk associated with Pro12Ala polymorphism of PPARγ gene [PDF]

Journal of Physiology and Biochemistry, 2002
Obesity in humans results from combined effects of genes, environment and lifestyles. A case-control study (obese vs. lean controls) was conducted to assess the possible association between obesity risk and the Pro12Ala polymorphism of the PPARg gene depending on the dietary intake.The study population comprised 313 Spanish subjects (66 men), which ...
Martinez, J.A. (José Alfredo), Martinez-Gonzalez, M.A. (Miguel Ángel), Forga, L. (Luis), Marti-del-Moral, A. (Amelia), Corbalan, M. (M.S.)   +4 more
openaire   +3 more sources

Determinación del polimorfismo pro12ala en el receptor activado por proliferadores de peroxisomas gamma-2 en pacientes que padecen diabetes mellitus tipo 2

Tecnociencia
La diabetes mellitus es un grupo de trastornos metabólicos comunes que comparten el fenotipo de hiperglucemia. El polimorfismo Pro12Ala en el exón B del gen que codifica para PPARg2 ha sido asociado en algunas poblaciones con diabetes tipo 2.
Evelyn Visuete , Tomás A. Diez , Edgardo Castro, Magaly de Chial, Ana E. Tejada , Carlos W. Ramos D.   +5 more
doaj   +1 more source

UEG Week 2023 Moderated Posters

, 2023
United European Gastroenterology Journal, Volume 11, Issue S8, Page 201-534, October 2023.
wiley   +1 more source

The common PPAR-γ2 Pro12Ala variant is associated with greater insulin sensitivity [PDF]

European Journal of Human Genetics, 2004
Several genetic variants of peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) have been identified, among which Pro12Ala, a missense mutation in exon 2, is highly prevalent in Caucasian populations. Up to now, conflicting results with regard to the association between this mutation and complex traits, such as obesity, insulin sensitivity ...
BUZZETTI, Raffaella, PETRONE, ANTONIO, M. C. Ribaudo, I. Alemanno, S. Zavarella, C. A. Mein, F. Maiani, TIBERTI, Claudio, BARONI, Marco Giorgio, VECCI, Elio Giancarlo, ARCA, Marcello, LEONETTI, Frida, DI MARIO, Umberto   +12 more
openaire   +2 more sources

Dietary patterns, insulin sensitivity and inflammation in older adults. [PDF]

, 2012
Background/objectivesSeveral studies have linked dietary patterns to insulin sensitivity and systemic inflammation, which affect risk of multiple chronic diseases.
Anderson, AL, Harris, TB, Houston, DK, Kanaya, AM, Lee, JS, Perry, SE, Sahyoun, NR, Tylavsky, FA   +7 more
core   +2 more sources

Alcohol intake modulates the genetic association between HDL cholesterol and the PPARγ2 Pro12Ala polymorphism

Journal of Lipid Research, 2005
The peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala polymorphism affects plasma lipids, but to what extent alcohol intake interferes with this association remains unknown.
Stefan-Martin Brand-Herrmann, Tatiana Kuznetsova, Andreas Wiechert, Katarzyna Stolarz, Valerie Tikhonoff, Klaus Schmidt-Petersen, Ralph Telgmann, Edoardo Casiglia, Ji-Guang Wang, Lutgarde Thijs, Jan A. Staessen, Eva Brand   +11 more
doaj   +1 more source

The C1431T polymorphism of peroxisome proliferator activated receptor γ (PPARγ) is associated with low risk of diabetes in a Pakistani cohort [PDF]

, 2016
BACKGROUND: Diabetes is a socioeconomic burden in Pakistan. International diabetes federation reported 6.9 million cases of diabetes and 87,548 deaths due to diabetes in Pakistan in 2014.
Huma Butt, null Shabana, Shahida Hasnain
core   +1 more source

Association of Bone Disorder and Gene Polymorphism of PPAR-γ Pro12 Ala in Egyptian Children with β-Thalassemia

Thalassemia Reports, 2023
β-thalassemia is a genetic disorder affecting chromosome 16, inherited from one or both parents. In spite of the improved treatment of the hematological disorder and its complications, β-thalassemic patients still exhibit an imbalance in bone mineral ...
Ahmed M. Abdel Hamied, Heba Mostafa Ahmed, Dina H. Eldahshan, Dalia S. Morgan, Abdel Meged A. Abdel Meged, Marwa O. Elgendy, Mohamed S. Imam, Turki A. H. Alotaibi, Majed M. S. Alotaibi, Manal T. N. Alotaibi, Sarah S. S. Alshalan, Sara O. Elgendy   +11 more
doaj   +1 more source