Personalised Nutrition in Obesity and Prediabetes: Do Genotypes Matter? [PDF]
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The interaction of breastfeeding and genetic factors on childhood obesity. [PDF]
Danaie M +14 more
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Research progress on the mechanistic impact of single-nucleotide polymorphisms and dietary pattern interactions on overweight and obesity in Chinese adults: a narrative review. [PDF]
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Multiomics: the intersection of personalized nutrition in cardiometabolic diseases. [PDF]
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Pro12Ala Polymorphism in PPARγ2 Associated with Depression in Chinese Nonagenarians/Centenarians
Archives of Medical Research, 2009The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARgamma) has been associated with decreased obesity, insulin resistance, type 2 diabetes and other age-associated diseases such as cognitive impairment, hypertension, cancer, osteoarthritis. Each one of these diseases had been linked to depression.
Huang Chang-Quan, Dong Bi-Rong
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Quantitative evaluation of PPAR-γ2 Pro12Ala polymorphism with hypertension
Herz, 2017The peroxisome proliferator-activated receptor γ2 (PPARγ2)Pro12Ala polymorphism has been reported to be associated with hypertension. However, relevant studies have shown inconsistent results.To quantitatively evaluate the relationship between the PPARγ2Pro12Ala polymorphism and hypertension risk, we conducted a meta-analysis based on all available ...
W, Yang, J, Wang, W, Ye, X, Li
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Interaction Between Pro12Ala Polymorphism of PPARγ2 and Diet on Adiposity Phenotypes
Current Atherosclerosis Reports, 2014The aim of this report is to perform a systematic review and qualitative synthesis of the literature to address whether, and to what extent, diet modulates the effects of the Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma 2 (PPARγ2) on body weight and other measures of adiposity.
LAPICE, EMANUELA, VACCARO, OLGA
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No evidence of a role for PPAR?? Pro12Ala polymorphism in endometrial cancer susceptibility
Pharmacogenetics, 2004Endogenous oestrogens play a crucial role in endometrial cancer pathogenesis, with most endometrial cancer risk factors causing an increase in oestrogens. Adipose tissue, where androgens are converted to oestrogens by the enzyme aromatase, is an important source of endogenous oestrogen production in the postmenopausal woman. The peroxisome proliferator-
Randi A, Paynter +4 more
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Association of Pro12Ala polymorphism of PPARγ gene with insulin resistance and related diseases
Diabetes Research and Clinical Practice, 2004To clarify the contribution of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma (PPARgamma) gene to susceptibility to insulin resistance and related diseases, 505 unrelated Japanese subjects were investigated, including 175 normotensive non-diabetic (NN) subjects, 125 normotensive diabetic (ND) subjects, 102 ...
Mayumi, Horiki +7 more
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The association of Pro12Ala polymorphism in PPARγ2 with lower carotid artery IMT in Japanese
Diabetes Research and Clinical Practice, 2003In this study, the association of the Pro12Ala peroxisome proliferator-activated receptor gamma2 (PPARgamma2) polymorphism with atherosclerosis was examined in a Japanese Type 2 diabetic population. PPARgamma has been identified as a key regulator of adipogenesis.
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