Results 141 to 150 of about 1,172 (173)
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[Is obesity associated with a polymorphism Pro12Ala and Pro115Gln in PPARgamma gene?].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004Gene PPARgamma is one of the pivotal factors that influence adipocyte differentiation. It is transcriptional factor that plays a crucial role in the regulation of genes involved in lipid utilisation and storage as well as insulin action. The aim of this study was to evaluate whether PPARgamma Pro12Ala and Pro115Gln polymorphisms are connected with ...
Bozena, Bidzińska +5 more
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Association between PPAR-γ2 Pro12Ala polymorphism and obesity: a meta-analysis
Molecular Biology Reports, 2014The peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) gene has been reported in the pathogeny of obesity. However, the results have been inconsistent. The purpose of this meta-analysis was to acquire a more accurate assessment of the association between PPAR-γ2 Pro12Ala polymorphism and obesity.
Ying-Shui, Yao +4 more
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PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes
Neuroscience Letters, 2008The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARG; NCBI dbSNP rs1801282) has been associated with preservation of cognitive function, decreased risk of diabetes, and increased risk of obesity. We attempted to replicate these associations, testing cognitive function and lifetime cognitive change in 519 participants who
Wendy, Johnson +4 more
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Increased insulin clearance in peroxisome proliferator-activated receptor γ2 Pro12Ala
Metabolism, 2003The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPARgamma(2)) is associated with reduced risk for type 2 diabetes. Although increased insulin sensitivity of glucose disposal and lipolysis has been reported, the exact mechanism by which the risk reduction is conferred is not clear.
Otto, Tschritter +11 more
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An age-dependent diet-modified effect of the PPARγ Pro12Ala polymorphism in children
Metabolism, 2011Variation in the peroxisome proliferator-activated receptor γ gene alters the risk for adiposity in adults, with evidence of interaction with diet. We investigated the age-related association between the Pro12Ala variant (rs1801282) and diet in obesity-related traits in children. The Pro12Ala variant was assayed in 2102 young children aged 1 to 6 years
Dedoussis, George V. +11 more
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Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis
Neuroscience Letters, 2009PPARs belong to a receptor family of ligand-activated transcription factors involved in the regulation of inflammation. A crucial role both for PPARgamma and for PPARalpha for the regulation of autoimmunity has been clearly demonstrated, as receptor agonists had beneficial effects on several CD4(+) T cell mediated autoimmune diseases including ...
Luisa, Klotz +4 more
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Der PPARγ-Pro12Ala-Polymorphismus und metabolisches Syndrom
2006The burden of chronic diseases, e. g. coronary heart diseases and diabetes, is rapidly increasing worldwide. Coronary heart diseases and diabetes are connected with lifestyle and dietary patterns. However, the genetic background in the pathogenesis of these diseases is considered to be important too. Because of that complex interplay these diseases are
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SP436 – The Pro12Ala polymorphism of PPARG gene and OSAHS
Otolaryngology - Head and Neck Surgery, 2009Shan-Kai Yin, Hai-Bo Shi, Jian Guan
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Effect of the Pro12Ala polymorphism of the PPARg2 gene on serum adiponectin changes.
Endocrine, 2006The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma 2 (PPARgamma2) gene and adiponectin, a protein secreted from adipose tissue, have been associated with insulin sensitivity. The present study demonstrates that in Finnish servicemen who were on a high-caloric diet for 6 mo only subjects with the Ala 12 allele of ...
Firoozeh, Mousavinasab +7 more
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