Results 121 to 130 of about 3,465 (237)

Pharmacogenetics in type 2 diabetes:Influence on response to oral hypoglycemic agents [PDF]

, 2016
Adem Yesuf Dawed, Kaixin Zhou, Ewan Robert Pearson  Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, Scotland, UK Abstract: Type 2 diabetes is one of the leading causes of morbidity ...
Dawed, Adem Yesuf, Pearson, Ewan Robert, Zhou, Kaixin   +2 more
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EFFECTIVENESS OF TREATMENT WITH PІOGLITAZONE IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND CONCOMITANT METABOLIC SYNDROME DEPENDING ON PRESENCE RS 1801282 (PRO12ALA) POLYMORPHISM IN GENE PPAR-γ

Медична наука України, 2019
Relevance. Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease on the one hand, and on the other, remains an unnoticed significant risk factor for cardiovascular disease.
V.P. Shypulin, L.M. Parunyan, V.V. Tishhenko, О.К. Kolyada, O.M. Ponomarov, N.G. Melnyk   +5 more
doaj   +1 more source

The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]

, 2014
Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
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Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 ( [PDF]

, 2007
AIMS/HYPOTHESIS: Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes and reduced insulin secretion. The transcription factor TCF7L2 is an essential factor for glucagon-like peptide-1 (GLP-1) secretion from
S. A. Schäfer, O. Tschritter, F. Machicao, C. Thamer, N. Stefan, B. Gallwitz, J. J. Holst, J. M. Dekker, L. M. t’Hart, G. Nijpels, T. W. van Haeften, H. U. Häring, A. Fritsche, SF Grant, M Stumvoll, C Schwanstecher, GR Chandak, JV Vliet-Ostaptchouk, R Saxena, CM Damcott, C Zhang, JC Florez, LJ Scott, I Reynisdottir, S Cauchi, A Helgason, F Yi, A Fritsche, D Tripathy, LM ‘t Hart, JB Ruige, TW Haeften van, A Fritsche, M Stumvoll, O Tschritter, M Olivier, CF Deacon, M Matsuda, S Papadopoulou, L Hansen, DA D’Alessio   +40 more
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The Genetic Bases of Type 2 Diabetes Mellitus [PDF]

, 2002
The pathogenesis of type 2 diabetes mellitus (T2DM) is complex, but it is secondary to a combination of insulin resistance and pancreatic beta-cell dysfunction that manifests itself as inadequate insulin secretion in the face of hyperglycemia.
Reis, André Fernandes, Velho, Gilberto
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Association of Peroxisome Proliferator-Activated Receptor.GAMMA. Gene Pro12Ala and C161T Polymorphisms With Metabolic Syndrome

Circulation Journal, 2007
BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARgamma) is involved mainly in adipocyte differentiation and has been suggested to play an important role in the pathogenesis of insulin resistance (IR) and atherosclerosis. The frequencies of 2 common polymorphisms of the PPARgamma gene, Pro12Ala single nucleotide polymorphism (SNP) in ...
Liu, Dongxia, Hua, Qi, Liu, Lisong, Guo, Jincheng   +3 more
openaire   +3 more sources

The association between diabetic nephropathy and polymorphisms in PPARγ Pro12Ala and CCR5δ 32 genes in type 2 diabetes

The Egyptian Journal of Internal Medicine, 2013
Background Diabetic nephropathy is one of the debilitating complications of type 2 diabetes and the leading cause for end-stage renal disease requiring renal replacement therapy.
Asmaa I. Ahmed, Noha A. Osman, Mohamed M. NasrAllah, Manal M. Kamal   +3 more
doaj   +1 more source

Association study on peroxisome proliferator ⁃ activated receptor γ 2 gene polymorphism and sporadic Alzheimer's disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To study the association between peroxisome proliferator⁃activated receptor γ 2 (PPAR γ 2) gene polymorphism and the onset of sporadic Alzheimer's disease (SAD).
Wen HE, Su⁃fang XUE, Jian⁃ping JIA
doaj  

Impact of the PPAR-γ2 Pro12Ala Polymorphism and ACE Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: Evidence From BENEDICT [PDF]

, 2009
Salvatore De Cosmo, Nicola Motterlini, Sabrina Prudente, Fabio Pellegrini, Roberto Trevisan, Antonio Bossi, Giuseppe Remuzzi, Vincenzo Trischitta, Piero Ruggenenti, on behalf of the BENEDICT Study Group   +9 more
openalex   +1 more source

Homeostasis del peso corporal: Factores genéticos [PDF]

, 2007
Se habla del componente hereditario de la regulación del peso corporal. Los datos de los que se dispone en la actualidad sugieren que entre el 40-70% de la variación en los fenotipos de ganancia de peso/obesidad está mediada genéticamente.
Marti, A. (Amelia)
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