Results 111 to 120 of about 3,465 (237)

Study on distribution of Pro12Ala single nucleotide polymorphism of PPARγ2 gene in randomly sampled diabetic population from Guwahati city

Italian Journal of Medicine, 2014
Diabetes is one of the most fatal and vastly heritable metabolic disorders across the globe primarily due to the associated long-term effects including uncontrolled blood sugar levels, blindness, renal and cardiac problems.
Navaneeta Majumdar, Ananya Bhowmick, Purabi Sarkar, Rhituraj Doley, Indrajit Kalita, Subhash S. Medhi, Sofia Banu   +6 more
doaj   +1 more source

ASSOCIATION BETWEEN PRO12ALa POLYMORPHISM OF PPARγ2 GENE AND CORONARY ARTERY DISEASE IN IRANIAN POPULATION WITH TYPE TWO DIABETES MELLITUS. [PDF]

Acta Endocrinol (Buchar), 2022
Saremi L, Lotfipanah S, Feizy F, Ghaffari ME, Babaniamansour S, Saltanatpour Z.   +5 more
europepmc   +1 more source

Зміни секреторної активності адипоцитів та вмісту ліпідів під впливом лікування хворих на артеріальну гіпертензію та ожиріння. Роль поліморфізму генів [PDF]

, 2014
Досліджено динаміку лептину, адипонектину та ліпідів у 110 хворих на есенційну артеріальну гіпертензію і абдомінальне ожиріння під впливом комплексного лікування залежно від поліморфізму генів ядерного рецептора g2 активатора проліферації пероксисом ...
Сидорчук, Лариса Петрівна, Соколенко, Аліна Андріївна, Соколенко, М.О.   +2 more
core  

Diet and PPARG2 Pro12Ala Polymorphism Interactions in Relation to Cancer Risk: A Systematic Review. [PDF]

Nutrients, 2021
Tran L, Bobe G, Arani G, Zhang Y, Zhang Z, Shannon J, Takata Y.   +6 more
europepmc   +1 more source

The Mediterranean diet protects against waist circumference enlargement in 12Ala carriers for the PPARgamma gene: 2 years' follow-up of 774 subjects at high cardiovascular risk. [PDF]

, 2009
The PPARgamma gene regulates insulin sensitivity and adipogenesis. The Pro12Ala polymorphism of this gene has been related to fat accumulation. Our aim was to analyse the effects of a 2-year nutritional intervention with Mediterranean-style diets on ...
Corella, D. (Dolores), Marti, A. (Amelia), Martinez, J.A. (José Alfredo), Martinez-Gonzalez, M.A. (Miguel Ángel), Razquin, C. (Cristina), Santos-Lozano, J.M. (José M.)   +5 more
core  

Early influences on cardiovascular and renal development [PDF]

, 2010
International audienceThe hypothesis that a developmental component plays a role in subsequent disease initially arose from epidemiological studies relating birth size to both risk factors for cardiovascular disease and actual cardiovascular disease ...
J. J. Miranda Geelhoed, Vincent W. V. Jaddoe   +1 more
core   +5 more sources

Evaluation of single nucleotide polymorphisms of Pro12Ala in peroxisome proliferator-activated receptor-γ and Gly308Ala in tumor necrosis factor-α genes in obese Asian Indians: a population-based study

Diabetes, Metabolic Syndrome and Obesity, 2010
Namita Bhagat1,2, Mukta Agrawal1, Kalpana Luthra3, Naval K Vikram4, Anoop Misra4, Rajeev Gupta21Department of Home Science, University of Rajasthan, Jaipur, Rajasthan, India; 2Department of Medicine, Fortis Escorts Hospital, Jaipur, Rajasthan, India ...
Gupta R
doaj  

Effects of the PPARG gene polymorphisms on markers of obesity and the metabolic syndrome in Bosnian subjects [PDF]

Journal of Medical Biochemistry, 2014
Background: Peroxisome proliferator-activated receptor gamma (PPARg) is a key transcription factor in adipogenesis, and also regulates a number of genes associated with lipid storage and insulin sensitivity.
Dujić Tanja, Bego Tamer, Mlinar Barbara, Semiz Sabina, Malenica Maja, Prnjavorac Besim, Ostanek Barbara, Marc Janja, Čaušević Adlija   +8 more
doaj  

Animal Models of GWAS-Identified Type 2 Diabetes Genes [PDF]

, 2013
More than 65 loci, encoding up to 500 different genes, have been implicated by genome-wide association studies (GWAS) as conferring an increased risk of developing type 2 diabetes (T2D).
Bellomo, EA, French, PM, McGinty, JA, Rutter, GA, Xavier, GDS   +4 more
core   +1 more source

Differential effects of the C1431T and Pro12Ala PPARγ gene variants on plasma lipids and diabetes risk in an Asian population

Journal of Lipid Research, 2004
We investigated the association of C1431T and Pro12Ala polymorphisms at the peroxisome proliferator-activated receptor γ (PPARγ) locus with plasma lipids and insulin resistance-related variables, according to diabetes status, in a large and ...
E. Shyong Tai, Dolores Corella, Mabel Deurenberg-Yap, Xian Adiconis, Suok Kai Chew, Chee Eng Tan, Jose M. Ordovas   +6 more
doaj   +1 more source