Journal of Diabetes Investigation, Volume 11, Issue 6, Page 1686-1703, November 2020.
wiley +1 more source
Ziablytsev S. V., Mokrii V. Y., Crystal M. V. The value of polymorphism RRO12ALA gene PPARG in violation of lipid peroxidation and antioxidant protection in patients with type 2 diabetes mellitus. Journal of Education, Health and Sport.
S. V. Ziablytsev +2 more
doaj +3 more sources
The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians [PDF]
One thousand thirty-eight normal glucose-tolerant and 1031 type 2 diabetic subjects selected from the Chennai Urban Rural Epidemiology Study were genotyped using polymerase chain reaction-restriction fragment length polymorphism assay to investigate ...
Bodhini, D +4 more
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Ueg Week 2020 Poster Presentations
United European Gastroenterology Journal, Volume 8, Issue S8, Page 144-887, October 2020.
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Pro12Ala PPAR γ2 gene polymorphism in PCOS women: the role of compounds regulating satiety
Five to ten percent of women of reproductive age suffer from polycystic ovary syndrome (PCOS). Leptin, NPY, galanin, cholecystokinin (CCK) are involved in the regulation of eating behavior. PPARγ are receptors that are probably involved in hyperandrogenism. This study was designed to assess associations between the Pro12Ala PPARγ2 gene polymorphism and
Bożena, Bidzińska-Speichert +5 more
openaire +2 more sources
THE ASSOCIATION OF GENE POLYMORPHISMS WITH ATHLETE STATUS IN UKRAINIANS [PDF]
Athletic performance is a polygenic trait influenced by both environmental and genetic factors. Objective: to investigate individually and in combination the association of common gene polymorphisms with athlete status in Ukrainians.
Ildus I. Ahmetov +3 more
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Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]
"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
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Enhanced role of PPARg with the Pro12Ala polymorphism
Obesity and type 2 diabetes mellitus (T2D) are two major public health problems that have motivated the scientific community to investigate the high contribution of genetic factors to these disorders. The peroxisome proliferator activated by gamma 2 (PPARg2) plays an important role in the lipid metabolism.
Fernandes, Rúben +3 more
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PPARγ2 Pro12Ala Polymorphism is Associated in Children With Traits Related to Susceptibility to Type 2 Diabetes. [PDF]
Vales-Villamarín C +5 more
europepmc +1 more source
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes [PDF]
Peroxisome proliferator-activated receptor gamma (PPARG) is a master transcriptional regulator of adipocyte differentiation and a canonical target of antidiabetic thiazolidinedione medications.
Altshuler, David
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