Results 81 to 90 of about 3,465 (237)
Pediatric Obesity, Volume 20, Issue 3, March 2025.Summary Background Although the genetic interplay with the environment has a major impact on obesity development, little is known on whether breastfeeding could modulate the genetic predisposition to obesity. Objectives To investigate whether breastfeeding attenuates the effect of an obesity genetic risk score (GRS) on adiposity in European adolescents.
Georgios K. Baxevanis +20 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 69, Issue 3, February 2025.No robust evidence for associations between TCF7L2, PPARγ, or KCNJ11 genotypes and postprandial insulin AUC after an oral glucose tolerance test (OGTT) was found. ABSTRACT Scope: Insulin responses to standardized meals differ between individuals. This variability may in part be explained by genotype.
Carmen P. S. Blanken +4 more
wiley +1 more source
The Ala/Ala genotype of PPARY Pro12 Ala polymorphism is associated with late onset of multiple sclerosis [PDF]
Archives of Biological Sciences, 2013 The function of peroxisome proliferator-activated receptor γ (PPARγ) in immune regulation, as well as in antiinflammatory and anti-proliferative actions towards T lymphocytes, has been reported. A potential role of PPARs in multiple sclerosis (MS) was
Lukić N. +6 more
doaj +1 more source
Exploration, Volume 4, Issue 5, October 2024.The coexistence of diabetes mellitus (DM) and tuberculosis (TB) presents a significant global burden, with DM being recognized as a major risk factor for TB. This review comprehensively analyzes the immunological aspects of DM‐TB comorbidity, shedding light on the impact of DM on TB pathogenesis and immune responses.
Zhaoyang Ye +6 more
wiley +1 more source
, 2009 Background: Peroxisome proliferator-activated receptor 2 (PPAR2) is a nuclear receptor that regulates adipocyte differentiation, lipid metabolism, and insulin sensitivity.
Akrami, S.M. +6 more
core +1 more source
Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction [PDF]
, 2009 Despite remarkable progress in diagnosis and understanding of risk factors, cardiovascular disease (CVD) remains still the leading cause of morbidity and mortality in the world\u27s developed countries.
Andreassi, Maria Grazia
core +1 more source
Ukrainian Scientific Medical Youth Journal, 2016 Resume. The incidence of type 2 diabetes is increasing in Ukraine and worldwide. The severity of this disease is determined by the number of complications, which are based on lipid peroxidation (LPO).
V. Y. Mokrii +2 more
doaj +1 more source
Association of FTO and PPARG polymorphisms with obesity in Portuguese women [PDF]
, 2013 Purpose: We evaluated the association between risk of obesity in the Portuguese population and two obesity-related single-nucleotide gene polymorphisms: fat-mass and obesity-associated (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma (
Baptista, Pedro Viana +6 more
core +1 more source
BMC Medical Genetics, 2005 Background The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator-Activated Receptor gamma 2 (PPAR-gamma 2) has been associated with insulin resistance and type 2 diabetes (T2D) and also inconsistently with obesity.
Charles Marie-Aline +8 more
doaj +1 more source
The Association of PPARγ Pro12Ala and C161T Polymorphisms with Polycystic Ovary Syndrome and Their Influence on Lipid and Lipoprotein Profiles [PDF]
International Journal of Fertility and Sterility, 2018 Background The aim of present study was to clarify the role of the peroxisome proliferator-activated receptor (PPAR) γ Pro12Ala and C161T polymorphisms in the pathogenesis of polycystic ovary syndrome (PCOS) and their influence on lipid and ...
Zohreh Rahimi +5 more
doaj +1 more source