Results 71 to 80 of about 3,465 (237)

Association of the PPARγ2 Pro12Ala polymorphism with increased risk of cardiovascular diseases

open access: yesGenetics and Molecular Research, 2015
This meta-analysis investigated the correlation between the PPARγ2 Pro12Ala polymorphism and cardiovascular disease (CVD). Electronic database and manual searches were conducted to retrieve studies published relevant to the PPARγ2 Pro12Ala polymorphism and CVD.
Y, Li, J, Zhu, J Q, Ding
openaire   +2 more sources

Assessment of association between the Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications

open access: yesZaporožskij Medicinskij Žurnal, 2019
Aim – to determine the association between Pro12Ala polymorphism of PPAR-γ gene with the risk of obstetric complications. Materials and methods. A total of 97 women with normal prepregnancy weight, singleton pregnancy, delivery at 37 weeks or more and
S. O. Ostafiichuk
doaj   +1 more source

PPAR α and PPAR γ Polymorphisms as risk factors for Dyslipidemia in a Chinese han population [PDF]

open access: yes, 2014
BACKGROUND: The PPAR α and PPAR γ are the key messengers responsible for the translation of nutritional stimuli into changes for the expression of genes, particularly genes involved in lipid metabolism.
Ming Wu   +4 more
core   +1 more source

Association of the polycystic ovary syndrome with genomic variants related to insulin resistance, type 2 diabetes mellitus, and obesity [PDF]

open access: yes, 1982
7 pages, 2 tables.-- Results from this work were presented at the 85th Annual Meeting of The Endocrine Society, Philadelphia, PA, June 2003.We have evaluated the possible association of polycystic ovary syndrome (PCOS) with 15 genomic variants ...
San Millán, José L.   +5 more
core   +1 more source

PPAR-Gamma Pro12Ala Polymorphism and Gastric Cancer Risk in a Turkish Population

open access: yesAsian Pacific Journal of Cancer Prevention, 2012
Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand dependent transcription factor involved in various processes, including carcinogenesis. We aimed to investigate any possible association of the PPARγPro12Ala (rs1801282) polymorphism with risk of developing gastric cancer (GC).A hospital based case control study was designed covering ...
Emel, Canbay   +9 more
openaire   +3 more sources

Dietary patterns, insulin sensitivity and inflammation in older adults. [PDF]

open access: yes, 2012
Background/objectivesSeveral studies have linked dietary patterns to insulin sensitivity and systemic inflammation, which affect risk of multiple chronic diseases.
Anderson, AL   +7 more
core   +2 more sources

Pharmacogenetics of oral antidiabetic drugs [PDF]

open access: yes, 2013
Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register
Becker, Matthijs L.   +2 more
core   +5 more sources

Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In‐Depth Review

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
The main objective of this review is to explore the impact of variation within the microbiome and among genes on nutrient metabolism and argue in favor of successful evidence of individualized dietary intervention for cardiovascular disease, diabetes, and obesity.
Muhammad Tayyab Arshad   +7 more
wiley   +1 more source

Peroxisome proliferator-activated receptor-γ (PPARγ) Pro12Ala polymorphism and risk for pediatric obesity [PDF]

open access: yesClinical Chemistry and Laboratory Medicine, 2009
Variation in the peroxisome-proliferator-activated receptor gamma (PPARgamma) gene has been reported to alter the risk for adiposity in adults.We investigated the gender related association between the Pro12Ala variant (rs1801282) in obesity and insulin resistance traits in 794 peri-adolescent children aged 10-12 years of Greek origin from the Gene and
George V, Dedoussis   +6 more
openaire   +2 more sources

The Single Nucleotide Polymorphism PPARG2 Pro12Ala Affects Body Mass Index, Fat Mass, and Blood Pressure in Severely Obese Patients

open access: yesJournal of Obesity, 2018
Background. The PPARG2 Pro12Ala (rs1801282) and IL6 -174G >C (rs1800795) have important function in body weight regulation and a potential role in obesity risk. We aimed to investigate the association between PPARG2 Pro12Ala and IL6 -174G >C variants and
Ana Paula dos Santos Rodrigues   +4 more
doaj   +1 more source

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