Results 51 to 60 of about 3,465 (237)

Peroxisome proliferator activated receptor gamma polymorphism Pro12Ala in polycystic ovary syndrome (PCOS) of South Indian Population

Asian Pacific Journal of Reproduction, 2016
Objective: To investigate the frequency of Pro12Ala polymorphism in PPAR gamma gene among PCOS of South Indian Population. Understanding this polymorphism may help us in better diagnosis prevention and therapeutic approaches towards management of PCOS ...
Raichel Jacob, Chandirasekar Ramachandran, Calistus Jude, Uthayakumar Venkatachalam, Sasikala Keshav Rao   +4 more
doaj   +1 more source

Association study of rs1801282 PPARG gene polymorphism and immune cells and cytokine levels in a Spanish pregnant women cohort and their offspring

Journal of Biomedical Science, 2020
Background Peroxisome proliferator activated receptor gamma (PPARG) belongs to the nuclear receptor superfamily functioning as transcription factors to regulate cellular differentiation, development and metabolism. Moreover, it has been implicated in the
Maria García-Ricobaraza, Mercedes García-Bermúdez, Francisco J. Torres-Espinola, M. Teresa Segura Moreno, Mathieu N. Bleyere, Ligia E. Díaz-Prieto, Esther Nova, Ascensión Marcos, Cristina Campoy   +8 more
doaj   +1 more source

Association of Bone Disorder and Gene Polymorphism of PPAR-γ Pro12 Ala in Egyptian Children with β-Thalassemia

Thalassemia Reports, 2023
β-thalassemia is a genetic disorder affecting chromosome 16, inherited from one or both parents. In spite of the improved treatment of the hematological disorder and its complications, β-thalassemic patients still exhibit an imbalance in bone mineral ...
Ahmed M. Abdel Hamied, Heba Mostafa Ahmed, Dina H. Eldahshan, Dalia S. Morgan, Abdel Meged A. Abdel Meged, Marwa O. Elgendy, Mohamed S. Imam, Turki A. H. Alotaibi, Majed M. S. Alotaibi, Manal T. N. Alotaibi, Sarah S. S. Alshalan, Sara O. Elgendy   +11 more
doaj   +1 more source

Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine [PDF]

, 2019
Type 2 diabetes mellitus (T2DM) is a chronic disease that has reached the levels of a global epidemic. In order to achieve optimal glucose control, it is often necessary to rely on combination therapy of multiple drugs or insulin because uncontrolled ...
Andreozzi, F, Mannino, Gc, Sesti, G
core   +1 more source

The Effect of PPARγ rs1801282 Variant on Mortality Risk Among Asians With Chronic Kidney Disease: A Cohort Study and Meta-Analysis

Frontiers in Genetics, 2022
Background: Chronic kidney disease (CKD) is a public health issue, and an independent risk factor for cardiovascular disease. The peroxisome proliferator-activated receptor gamma (PPARG) plays an important role in the cardiovascular system.
Wei-Teing Chen, Wei-Teing Chen, Chih-Chien Chiu, Dung-Jang Tsai, Dung-Jang Tsai, Pi-Shao Ko, Pi-Shao Ko, Meng-Chang Lee, Hsiao-Ting Lin, Ying-Kai Chen, Ying-Kai Chen, Wen Su, Yuh-Feng Lin, Yuh-Feng Lin, Sui-Lung Su   +14 more
doaj   +1 more source

FABP-2 and PPAR-γ Haplotype as Risk Factors for Dyslipidemia in a Type 2 Diabetes Mellitus Population of Santa Rosa del Conlara, San Luis, Argentina [PDF]

, 2014
Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by the interaction between genetic predisposition and environmental factors. Genetics plays an important role on lipid homeostasis. Many genes are involved in the lipid metabolism,
Fernandez, Gustavo, Gonzalez, Irma Ines, Ojeda, Marta Susana, Olmos Nicotra, Maria Florencia, Siewert, Susana Elfrida   +4 more
core   +1 more source

Genetic variants and the metabolic syndrome: a systematic review [PDF]

, 2011
Several candidate gene studies on the metabolic syndrome (MetS) have been conducted. However, for most single nucleotide polymorphisms (SNPs) no systematic review on their association with MetS exists.
Boer, J.M., Feskens, E.J.M., Povel, C.M.
core   +3 more sources

ROLE OF THE PPARГ PROI2ALA POLYMORPHISM IN HYPERTENSION AND METABOLIC SYNDROME

Евразийский Кардиологический Журнал, 2012
Aim. То study prevalence of Pro12Ala polymorphism of the PPARγ gene in Uzbek hypertensive patients and healthy men and its association with blood pressure and cardiovascular remodeling process. Methods.
R. D. Kurbanov, N. Z. Srojidinova
doaj   +1 more source

The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes [PDF]

, 2015
Cross-sectional studies suggest the association between diabetic nephropathy and the PPARγ2 Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 (PPARγ2).
BRUZZESE, DARIO, COCOZZA, SARA, COCOZZA, SERGIO, LAPICE, EMANUELA, Monticelli, Antonella, PINELLI, MICHELE, RICCARDI, GABRIELE, VACCARO, OLGA   +7 more
core   +1 more source

PPARγ2 Pro12Ala Polymorphism and Insulin Resistance in Japanese Hypertensive Patients

Hypertension Research, 2002
We investigated the relationship between peroxisome proliferator-activated receptor gamma (PPARgamma) Pro12Ala substitution and insulin resistance in subjects with normal insulin secretory capacity, since it has been reported that PPARgamma may affect not only insulin resistance but also insulin secretion.
Junko, Yamamoto, Shigeru, Kageyama, Masami, Nemoto, Takashi, Sasaki, Tatsuya, Sakurai, Ken-ichi, Ishibashi, Akira, Mimura, Kuninobu, Yokota, Naoko, Tajima   +8 more
openaire   +3 more sources