Results 181 to 190 of about 142,423 (312)

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

, 2016
The (pro)renin receptor ([P]RR) interacts with (pro)renin at concentrations that are >1000× higher than observed under (patho)physiological conditions. Recent studies have identified renin-angiotensin system-independent functions for (P)RR related to its
Zelcer, Noam, Scheij, S, Demmers, Jeroen, M-Dallinga-Thie, G, Dekkers, Dick H.W., Lu, Xifeng, Mulder, Monique T., Meima, Marcel E., Loregger, Anke, Dekkers, Dick, Demmers, Jeroen A.A., Danser, A. H. Jan, Sorrentino, V, Danser, A.H. Jan, Sorrentino, Vincenzo, Meima, Marcel, Nelson, Jessica K., Nelson, JK, Mulder, Monique, M-Dallinga-Thie, Geesje, Danser, Jan, Demmers, Jeroen A. A., Zelcer, N, Dekkers, Dick H. W., Scheij, Saskia, M.-Dallinga-Thie, Geesje, Loregger, A   +26 more
core   +1 more source

Proteomic and metabolic signatures of female reproductive factors and risk of age‐related ocular diseases: A large prospective cohort study

VIEW, EarlyView.
The full editable vector source file of this graphical abstract is uploaded as a supplementary EPS file for typesetting. All elements are copyright‐free. Abstract Age‐related ocular diseases (ARODs), including cataract, primary open‐angle glaucoma (POAG), and age‐related macular degeneration (AMD), are leading causes of vision impairment and exhibit ...
Linge Jian, Zhiqian Huang, Keke Zhang, Jing Lin, Jia You, Yi Lu, Xiangjia Zhu   +6 more
wiley   +1 more source

Increased Serum Soluble (Pro)renin Receptor Levels in Patients with Sarcopenia

International Journal of Endocrinology
Purpose. Sarcopenia is an advancing and widespread skeletal muscle condition characterized by the depletion of skeletal muscle mass. The (pro)renin receptor ((P)RR) is a multifaceted protein with both pathophysiological and physiological functions. (P)RR
Satoshi Morimoto, Haruki Sasaki, Chikahito Suda, Atsuhiro Ichihara, Nobuyuki Ura   +4 more
doaj   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews, Arron Lacey, Kate Bache, Emma J. Kidd   +3 more
wiley   +1 more source

Publisher Correction: Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis. [PDF]

Hypertens Res, 2023
Ebihara A, Sugihara D, Matsuyama M, Suzuki-Nakagawa C, Nabi AHMN, Nakagawa T, Nishiyama A, Suzuki F.   +7 more
europepmc   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Soluble (Pro)Renin Receptor Level in Patients with Severe Obesity Is Associated with Visceral Adiposity and Is Involved with Insulin Resistance and Renal Injury. [PDF]

Obes Facts, 2023
Yamaguchi T, Morimoto S, Suda C, Ichihara A, Ishihara N, Nakamura S, Tanaka S, Watanabe Y, Imamura H, Ohira M, Shimizu N, Saiki A, Tatsuno I.   +12 more
europepmc   +1 more source

Mapping the protein binding site of the (pro)renin receptor using in silico 3D structural analysis. [PDF]

Hypertens Res, 2023
Ebihara A, Sugihara D, Matsuyama M, Suzuki-Nakagawa C, Nabi AHMN, Nakagawa T, Nishiyama A, Suzuki F.   +7 more
europepmc   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

(Pro)Renin Receptor Decoy Peptide PRO20 Protects against Oxidative Renal Damage Induced by Advanced Oxidation Protein Products. [PDF]

Molecules, 2023
Fang H, Yang T, Zhou B, Li X.
europepmc   +1 more source