Results 201 to 210 of about 32,074 (246)

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Acute hot‐water immersion augments the diastolic blood pressure nocturnal dip in healthy adults

Experimental Physiology, EarlyView.
Abstract Hot‐water immersion (HWI) has been shown to reduce 24 h ambulatory systolic blood pressure in hypertensive adults and might represent a preventative strategy for maintaining cardiovascular health in normotensive adults. The purpose of this study was to determine the time course of post‐HWI hypotension and test the hypothesis that a single HWI ...
Samuel F. Leaney, Ferrida A. F. Ponce, Tomos F. Owen, Benjamin L. Harvey, Oliver N. Davies‐Wilson, Oliver M. A. Brand, Geoff B. Coombs, Jonathan P. Moore, Samuel J. Oliver   +8 more
wiley   +1 more source

Long‐term adverse cardiovascular changes induced by cocoa shell extract administration through lactation in fetal undernourished and control rats

Experimental Physiology, EarlyView.
Abstract Cocoa shell extract (CSE; rich in antioxidant compounds) administered to adult hypertensive rats exposed to fetal undernutrition (MUN) reduces blood pressure, improving cardiovascular alterations. We aimed to explore lactation as a reprogramming window, evaluating the long‐term effects of CSE supplementation during this period. MUN and control
Santiago Ruvira, Pilar Rodríguez‐Rodríguez, Metee Iampanichakul, Begoña Quintana‐Villamandos, Dolores Morales, David Ramiro‐Cortijo, Silvia M. Arribas   +6 more
wiley   +1 more source

ATP6ap2/(Pro)renin receptor

Shinzo, 2011
openaire   +1 more source

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The (pro)renin receptor and soluble (pro)renin receptor in choriocarcinoma

Reproduction, 2021
Abstract This study aimed to determine if the (pro)renin receptor (ATP6AP2) changes the cellular profile of choriocarcinomas from cytotrophoblast cells to terminally syncytialised cells and ascertain whether this impacts the invasive potential of choriocarcinoma cells.
Morosin, Saije K., Delforce, Sarah J., Kahl, Richard G. S., de Meaultsart, Celine Corbisier, Lumbers, Eugenie R., Pringle, Kirsty G.   +5 more
openaire   +2 more sources

The (pro)renin receptors

Journal of Molecular Medicine, 2008
Two (pro)renin receptors have been characterized so far, the mannose-6-phosphate receptor (M6P-R) and a specific receptor called (P)RR for (pro)renin receptor. Each receptor controls a different aspect of renin and prorenin metabolism. The M6P-R is a clearance receptor, whereas (P)RR mediates their cellular effects by activating intracellular signaling
Geneviève, Nguyen, Aurélie, Contrepas
openaire   +2 more sources

PLZF and the (pro)renin receptor

Journal of Molecular Medicine, 2008
For many years, angiotensin II with its respective receptors was considered to be the only effector molecule within the renin-angiotensin system. Nevertheless, several studies indicated that renin (the enzyme catalyzing the generation of angiotensin I) and its enzymatically inactive precursor prorenin may have an angiotensin-II-independent (patho ...
Jan H, Schefe, Thomas, Unger, Heiko, Funke-Kaiser   +2 more
openaire   +2 more sources

The (Pro)Renin Receptor and the Kidney

Seminars in Nephrology, 2007
Prorenin binding to the (pro)renin receptor not only causes a nonproteolytic activation of prorenin leading to the activation of the renin-angiotensin system (RAS), but also stimulates the receptor's own intracellular signaling pathways independent of the RAS.
Atsuhiro, Ichihara, Yuki, Kaneshiro, Tomoko, Takemitsu, Mariyo, Sakoda, Hiroshi, Itoh   +4 more
openaire   +2 more sources

Renin, Prorenin, and the (Pro)Renin Receptor

2009
The discovery of a receptor for renin and for its inactive precursor prorenin, and the introduction of renin inhibitors in therapeutic, has renewed the interest for the physiology of the renin angiotensin system (RAS) and has brought prorenin back in the spotlight.
Genevieve Nguyen, Aurelie Contrepas
openaire   +1 more source