Results 61 to 70 of about 3,622,028 (257)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Probability Distributions for Quantum Stress Tensors Measured in a Finite Time Interval

, 2015
A meaningful probability distribution for measurements of a quantum stress tensor operator can only be obtained if the operator is averaged in time or in spacetime. This averaging can be regarded as a description of the measurement process.
Fewster, Christopher J., Ford, L. H.
core   +1 more source

Filter Estimator Based on the Probability Distribution

IEEE Access
In this paper, we propose a model of a parameter estimator filter for Black Box-type Stochastic Systems (BBSS), that is, only its inputs and outputs are known; considering its intrinsic properties observed in the second probability moment, in which the ...
Romeo Urbieta Parrazalez, Rosaura Palma Orozco, Maria Teresa Zagaceta Alvarez, Jose Luis Fernandez Munoz, Karen Alicia Aguilar Cruz   +4 more
doaj   +1 more source

Funções de distribuição diamétrica em um fragmento de Floresta Ombrófila Mista Diametric distribution functions in a fragment of Mixed Ombrophylous Forest

Ciência Rural, 2009
Os objetivos deste estudo foram ajustar e selecionar funções de densidade probabilística que caracterizem a estrutura diamétrica desse fragmento e das espécies: Cedrela fissilis (Cedro), Luehea divaricata (Açoita Cavalo), Gochnatia polymorpha (Cambará ...
Sebastião do Amaral Machado, Alan Lessa Derci Augustynczik, Rodrigo Geroni Mendes Nascimento, Saulo Jorge Téo, Eder Pereira Miguel, Marco Aurélio Figura, Luís César Rodrigues da Silva   +6 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Extended Rayleigh Probability Distribution to Higher Dimensions

Journal of Probability and Statistics
In this paper, we have derived and studied new probability distributions by extending the 2-dimensional Rayleigh distribution (RD). First, we extend the RD to 3 dimensions and then generalize it to k dimensions for any positive integer k ≥ 3.
Adugna Gelaw Yirsaw, Ayele Taye Goshu
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Superdiffusion in Decoupled Continuous Time Random Walks

, 2000
Continuous time random walk models with decoupled waiting time density are studied. When the spatial one jump probability density belongs to the Levy distribution type and the total time transition is exponential a generalized superdiffusive regime is ...
Alexander, Batchelor, Blumen, Blumen, C. Budde, D. Prato, Grossmann, Klafter, M. Ré, Monin, Montroll, Montroll, Ott, Prato, Scher, Shlesinger, Shlesinger, Tsallis, Tsallis, Van Kampen, Zaslavsky, Zumofen   +21 more
core   +2 more sources

A New Index for Quantifying the Peakedness of a Probability Distribution

Mathematics
Peakedness is an important characteristic of probability distributions, and an effective method for quantifying peakedness is essential for statistical modeling and comparing different probability distributions in many practical applications.
Hening Huang
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source