Results 71 to 80 of about 1,784,102 (271)

Sampling Time Effects for Persistence and Survival in Step Structural Fluctuations

open access: yes, 2005
The effects of sampling rate and total measurement time have been determined for single-point measurements of step fluctuations within the context of first-passage properties.
C. Dasgupta   +11 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

WEIGHTING IMPORTANCE SAMPLING METHOD FOR STRUCTURAL TIME-DEPENDENT FAILURE PROBABILITY FUNCTION ESTIMATION

open access: yesJixie qiangdu, 2023
Time-dependent failure probability function(TDFPF) of parameters is one of the key problems of structural time-dependent reliability-based optimization.
QIAN YuGeng, YUAN XiuKai, CHEN JingQiang
doaj  

Variance estimation for measures of change in probability sampling

open access: yes, 2003
We propose to estimate the design variance of absolute changes between two cross-sectional estimators under rotating sampling schemes. We show that the variance estimator proposed is generally positive.
Berger, Yves G.
core  

Universal Sampling Rate Distortion

open access: yes, 2017
We examine the coordinated and universal rate-efficient sampling of a subset of correlated discrete memoryless sources followed by lossy compression of the sampled sources.
Boda, Vinay Praneeth, Narayan, Prakash
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

A simple variance estimator for unequal probability sampling without replacement

open access: yes, 2003
Survey sampling textbooks often refer to the Sen-Yates-Grundy variance estimator for use with without replacement unequal probability designs. This estimator is rarely implemented, because of the complexity of determining joint inclusion probabilities ...
Berger, Yves G.
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

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