Results 111 to 120 of about 257,741 (338)

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

Advanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding, Xingfu Bao, Ying Zhao, Lin Bai, Jinming Zhang, Chengjing Xu, Tianyan Chen, Shuang Dai, Yufu Liu, Min Hu, Meng Qin, Zhen Liu   +11 more
wiley   +1 more source

Influence of Dehydrated Wheat/Rice Cereal Matrices on Probiotic Activity of Bifidobacterium animalis ssp. lactis BB-12®

Food Technology and Biotechnology, 2019
Three novel dehydrated wheat/rice cereal functional products with an addition of well documented probiotic Bifidobacterium animalis ssp. lactis BB-12® (BB-12®) were developed in Podravka factory for the infants older than 4 months: instant rice cereal ...
Andreja Leboš Pavunc, Lenkica Penava, Jasmina Ranilović, Jasna Novak, Martina Banić, Katarina Butorac, Emilija Petrović, Vesna Mihaljević-Herman, Krešo Bendelja, Ana Savić Mlakar, Ksenija Durgo, Blaženka Kos, Jagoda Šušković   +12 more
doaj   +1 more source

Probiotics and allergy [PDF]

Proceedings of the Nutrition Society, 2005
Allergy is caused by an immune reaction that is out of all proportion to the antigenic stimuli. Classical allergy is a type I hypersensitivity reaction mediated by the interaction of mast cells (and eosinophils) coated with allergen-specific IgE and a cross-linking allergen.
openaire   +2 more sources

Secondary Bile Acids Modified by Odoribacter Splanchnicus Alleviate Colitis by Suppressing Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
In ulcerative colitis, the loss of Odoribacter splanchnicus disrupts a microbiota‐metabolite‐neutrophil axis. Restoring this bacterium boosts lithocholic acid, which suppress neutrophil extracellular trap formation and eases colonic inflammation.
Jing Xu, Jianhong Li, Xue Guo, Chen Huang, Yao Peng, Haoming Xu, Yingfei Li, Jingkui Xu, Jinxia Hu, Yitong Liao, Yuqiang Nie, Youlian Zhou   +11 more
wiley   +1 more source

Faecalibaculum rodentium Alleviates Ionizing Radiation‐Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate

Advanced Science, EarlyView.
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu, Hui Guo, Na Sun, Rui Xiao, Binbin Ji, Ruihan Jiang, Fuxing Dong, Chen Yao, Xuerong Wang, Rongqing Li, Jie Zhao, Xueqin Li, Shengzhe Gong, Yongqin Qin, Xin Chen, Yuchen Pan, Takayuki Ikezoe, Jing Yang   +17 more
wiley   +1 more source

Drosophila melanogaster as a High-Throughput Model for Host–Microbiota Interactions

Frontiers in Microbiology, 2017
Microbiota research often assumes that differences in abundance and identity of microorganisms have unique influences on host physiology. To test this concept mechanistically, germ-free mice are colonized with microbial communities to assess causation ...
Gregor Reid, Gregor Reid, Gregor Reid, Mark Trinder, Mark Trinder, Brendan A. Daisley, Brendan A. Daisley, Josh S. Dube, Josh S. Dube   +8 more
doaj   +1 more source

Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants. [PDF]

, 2017
Attempts to alter intestinal dysbiosis via administration of probiotics have consistently shown that colonization with the administered microbes is transient. This study sought to determine whether provision of an initial course of Bifidobacterium longum
Andra A. Hutton, Bethany M. Henrick, Carlito B. Lebrilla, Claire A. Shaw, Daniela Barile, David A. Mills, Gege Xu, Giorgio Casaburi, J. Bruce German, Jasmine C. C. Davis, Jennifer T. Smilowitz, Lindsey N. Contreras, Mark A. Underwood, Michelle C. Palumbo, Rosa Krajmalnik-Brown, Samara L. Freeman, Steven A. Frese   +16 more
core   +2 more sources

Intravenous iRGD‐Guided, RBC‐Membrane Camouflaged Lactococcus Lactis Remodels Cold NSCLC and Enhances PD‐1 Blockade

Advanced Science, EarlyView.
This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen, Junmeng Zhu, Xiao Liu, Jie Shao, Aoxing Chen, Yi Mei, Xinyin Zhang, Qinyi Chen, Lin Li, Baorui Liu   +9 more
wiley   +1 more source

Dietary Nitrate: Effects on the health of weaning pigs and Antimicrobial activity on seven probiotic Bifidobacterium spp. strains [PDF]

, 2007
The potential role of nitrite as an antimicrobial substance in the stomach may be of some importance in the ecology of the gastrointestinal tract and in host physiology. It has been shown that nitrite, under the acidic conditions of the stomach, may kill
Allesina, S., Barba, M., Biavati, B., Bosi, P., D'Aimmo, M. R., Deidda, F., Lorenzini, P., Mazzoni, M., Modesto, M., Stefanini, I., Strozzi, G. P., Tittarelli, C., Trevisi, P.   +12 more
core  

Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illness. [PDF]

, 2016
Purpose of reviewLoss of 'health-promoting' microbes and overgrowth of pathogenic bacteria (dysbiosis) in ICU is believed to contribute to nosocomial infections, sepsis, and organ failure (multiple organ dysfunction syndrome).
Knight, Rob, McDonald, Daniel, Wischmeyer, Paul E   +2 more
core   +2 more sources