Results 221 to 230 of about 166,330 (312)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Gut Enterococcus faecium derived leucic acid mediates the antiobesity effect of dietary fiber

open access: yesiMeta, EarlyView.
This study identified Enterococcus faecium as a gut bacterium with anti‐obesity activity, which alleviated adipocyte hypertrophy, dyslipidemia, and hepatic steatosis by converting leucine into leucic acid (LEA) to regulate mitochondrial oxidative phosphorylation.
Baifei Hu   +9 more
wiley   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang   +9 more
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

open access: yesInterdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang   +22 more
wiley   +1 more source

Prebiotics, probiotics, and synbiotics therapy in critically ill patients: a systematic review and network meta-analysis. [PDF]

open access: yesAnn Intensive Care
Hatakeyama J   +10 more
europepmc   +1 more source

Advancements and prospects in bioinformatics and omics for colorectal cancer: A dual bibliometric analysis of global trends and top cited publications

open access: yesJournal of Intelligent Medicine, EarlyView.
This dual bibliometric analysis examined 5129 publications and the top 100 most cited publications on bioinformatics and omics in colorectal cancer (2004–2025) from the Web of Science Core Collection. Using SCImago Graphica, VOSviewer, CiteSpace, and R Studio, we analyzed global trends, countries/regions, institutions, journals, authors, references ...
Yue Huang   +7 more
wiley   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow   +4 more
wiley   +1 more source

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