Results 241 to 250 of about 335,473 (338)

Two stable gut microbiome guilds predict liver tumor class and treatment responses

open access: yesiMeta, EarlyView.
Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu   +17 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Probiotics, gut microbiota, and their influence on host health and disease

open access: yesMolecular Nutrition & Food Research, 2017
J. Espín   +6 more
semanticscholar   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

Similarity and substitution: Using pile sorting methods to explore economic behavior

open access: yesJournal of the Agricultural and Applied Economics Association, EarlyView.
Abstract Despite the common intuition that similar products are stronger demand substitutes, this study shows a more nuanced relationship between perceived similarity and utility substitution. Using pile sorting, a method where items are sorted into groups according to their similarity, we conduct large‐scale consumer surveys on purchasing 21 foods for
Jayson L. Lusk   +2 more
wiley   +1 more source

Dual process for improved recovery of essential oil and pectin from citrus waste

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Citrus essential oils (EO), particularly orange essential oil (OEO) and pectin, are high‐value chemical products widely used across various industries, including pharmaceuticals, food and beverages, detergents, and cosmetics. These compounds are present in the residual by‐products generated by juice production industries, and their ...
Jorge Welti‐Chanes   +3 more
wiley   +1 more source

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