Results 131 to 140 of about 41,349 (293)

Noise Modeler: An Interactive Editor and Library for Procedural Terrains via Continuous Generation and Compilation of GPU Shaders

, 2015
Johan Klokkhammer Helsing, Anne C. Elster   +1 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Preliminary Poetics of Procedural Generation in Games

, 2019
Isaac Karth
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Sequential Human Assembly and Disassembly Motions in Human-Robot Coexisting Environments. [PDF]

Sci Data
Liu Z, Wang T, Ji Z, Xu W, Wang L, Wang XV.   +5 more
europepmc   +1 more source

Infinigen Indoors: Photorealistic Indoor Scenes using Procedural Generation [PDF]

Alexander Raistrick, Lingjie Mei, Karhan Kayan, David Yan, Yiming Zuo, Beining Han, Hongyu Wen, Meenal Parakh, Stamatis Alexandropoulos, Lahav Lipson, Zeyu Ma, Jia Deng   +11 more
openalex   +1 more source

Institutional Policies on Artificial Intelligence in Higher Education: Frameworks and Best Practices for Faculty

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores institutional policies on artificial intelligence (AI) in higher education. As AI tools become increasingly utilized in academia—from research and teaching to assessment and student support—institutions face growing pressure to establish clear, ethical, and practical guidelines to help guide faculty.
Lauren Azevedo, Pedro Robles, Eric Best, Daniel J. Mallinson   +3 more
wiley   +1 more source

Small Nodules and Big Questions: A Closer Look at the RELIANT Trial. [PDF]

Am J Respir Crit Care Med
Bertolaccini L, Bardoni C, Guarize J.
europepmc   +1 more source