Results 11 to 20 of about 130,011 (340)

Non-invasive instrumental analytical methods in modern pharmaceutical technology [PDF]

Farmacja Polska, 2020
The purpose of this work is the evaluation of the state of knowledge in the scope of the possibility of using of non-invasive analytical methods in the implementation of Process Analytical Technology strategy, which is currently recommended by worldwide ...
Joanna Ronowicz, Natalia Piekuś-Słomka
doaj   +1 more source

On-Line Real-Time Monitoring of a Rapid Enzymatic Oil Degumming Process: A Feasibility Study Using Free-Run Near-Infrared Spectroscopy

Foods, 2021
Enzymatic degumming is a well established process in vegetable oil refinement, resulting in higher oil yield and a more stable downstream processing compared to traditional degumming methods using acid and water. During the reaction, phospholipids in the
Jakob Forsberg, Per Munk Nielsen, Søren Balling Engelsen, Klavs Martin Sørensen   +3 more
doaj   +1 more source

Analytical QBD Approach to Redefine the Quality of Pharmaceuticals: A Review

Journal of Pharmaceutical Research, 2023
As per the present scenario traditional techniques of quality by testing of finished pharmaceutical products have proved to be unsatisfactory, although focus on 'Total quality assurance can be attained only by in-process testing and analysis ...
Shaik Ayesha Ameen, Nagaraju Pappula
doaj   +1 more source

Advancement of process control using process analytical technology (PAT) in continuous biomanufacturing: Case study [PDF]

, 2020
Sobhana Sripada, Krishnan Sushmitha, Rajan R. Bhawnani, Jessica Molek, Aparajith Bhaskar, Eduardo Lopez-Montero, John Mack   +6 more
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Real-time quality control for chemical and biotechnological processes: a brief review

Journal of Medical Science, 2023
Monitoring critical process parameters of chemical and biotechnological processes is an essential tool at every stage of drug manufacturing technology.
Agnieszka Kołodziejczak-Radzimska, Beata Rukowicz, Sharon Davin   +2 more
doaj   +1 more source

Fast and Non-Invasive Evaluation of Yeast Viability in Fermentation Processes Using Raman Spectroscopy and Machine Learning

Beverages, 2023
Fermentation processes used for producing alcoholic beverages such as beer, wine, and cider have a long history, having been developed early on across different civilizations. In most instances, yeast strains are used for fermentation processes, e.g., at
Raoul Heese, Jens Wetschky, Carina Rohmer, Susanne M. Bailer, Michael Bortz   +4 more
doaj   +1 more source

Process Analytical Technology Tools for Monitoring Pharmaceutical Unit Operations: A Control Strategy for Continuous Process Verification

Pharmaceutics, 2021
Various frameworks and methods, such as quality by design (QbD), real time release test (RTRT), and continuous process verification (CPV), have been introduced to improve drug product quality in the pharmaceutical industry.
Eun Ji Kim, Ji Hyeon Kim, Min-Soo Kim, Seong Hoon Jeong, Du Hyung Choi   +4 more
doaj   +1 more source

The Rocky Road to a Digital Lab

CHIMIA, 2023
The pharmaceutical industry has begun incorporating continuous manufacturing technology in synthetic routes toward active pharmaceutical ingredients (APIs).
Peter Sagmeister, Jason D. Williams, C. Oliver Kappe   +2 more
doaj   +1 more source

In Situ Quantification of Polyhydroxybutyrate in Photobioreactor Cultivations of Synechocystis sp. Using an Ultrasound-Enhanced ATR-FTIR Spectroscopy Probe

Bioengineering, 2021
Polyhydroxybutyrate (PHB) is a very promising alternative to most petroleum-based plastics with the huge advantage of biodegradability. Biotechnological production processes utilizing cyanobacteria as sustainable source of PHB require fast in situ ...
Philipp Doppler, Christoph Gasser, Ricarda Kriechbaum, Ardita Ferizi, Oliver Spadiut   +4 more
doaj   +1 more source

Measurement of Paracetamol Concentration Using an Erbium-Doped Fiber Ring Cavity

Photonics, 2023
Process Analytical Technology (PAT) has been increasingly used in the pharmaceutical industry to monitor essential parameters in real-time during pharmaceutical processes. The concentration of Active Pharmaceutical Ingredients (APIs), such as paracetamol,
Liliana Soares, Rosa Ana Pérez-Herrera, Susana Novais, António Ferreira, Susana Silva, Orlando Frazão   +5 more
doaj   +1 more source