Diamond-Coated Silicon ATR Elements for Process Analytics
Infrared attenuated total reflection (ATR) spectroscopy is a common laboratory technique for the analysis of highly absorbing liquids or solid samples.
Nicolai Arndt +4 more
doaj +1 more source
Challenges and Opportunities of Implementing Data Fusion in Process Analytical Technology—A Review
The release of the FDA’s guidance on Process Analytical Technology has motivated and supported the pharmaceutical industry to deliver consistent quality medicine by acquiring a deeper understanding of the product performance and process interplay.
Tibor Casian +5 more
doaj +1 more source
Stereolithography Cure Process Modeling Using Acrylate Resin [PDF]
In this paper, a complex stereolithography (SL) cure process model is presented that incorporates transient thermal and chemical effects which influence final part shape and properties.
Henderson, Clifford L. +3 more
core +1 more source
In the last few decades, hot-melt extrusion (HME) has emerged as a rapidly growing technology in the pharmaceutical industry, due to its various advantages over other fabrication routes for drug delivery systems. After the introduction of the ‘quality by
Nimra Munir +3 more
doaj +1 more source
Modelling the primary drying step for the determination of the optimal dynamic heating pad temperature in a continuous pharmaceutical freeze-drying process for unit doses [PDF]
In the pharmaceutical industry, traditional freeze-drying of unit doses is a batch-wise process associated with many disadvantages. To overcome these disadvantages and to guarantee a uniform product quality and high process efficiency, a continuous ...
Corver, Jos +8 more
core +1 more source
Twin-screw wet granulation (TSWG) is a method of continuous pharmaceutical manufacturing and a potential alternative method to batch granulation processes.
Jie Zhao, Geng Tian, Haibin Qu
doaj +1 more source
The ring-opening polymerization of D,L-lactide in the melt initiated with tetraphenyltin [PDF]
Melt polymerization conditions for D,L-lactide initiated with tetraphenyltin were studied with regard to polymer molecular weight and weight distributions.
Berg, J.W.A. van den +3 more
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Effect of particle size distribution on spatially and angularly resolved diffuse reflectance measurement [PDF]
Particle size distribution is vitally important in pharmaceutical formulation. Spectroscopy is the most prominent method for in-line particle measurements and process analytics, and near-infrared (NIR) spectroscopy can be seen as the workhorse in the ...
Chen, Yi-Chieh +5 more
core
Cross-Bridge Kelvin resistor structures for reliable measurement of low contact resistances and contact interface characterization [PDF]
The parasitic factors that strongly influence the measurement accuracy of Cross-Bridge Kelvin Resistor (CBKR) structures for low specific contact resistances (rhoc) have been extensively discussed during last few decades and the minimum of the rhoc value,
Klootwijk, J.H. +4 more
core +4 more sources

