Results 61 to 70 of about 128,839 (232)

Polydisperse Adsorption: Pattern Formation Kinetics, Fractal Properties, and Transition to Order

open access: yes, 1998
We investigate the process of random sequential adsorption of polydisperse particles whose size distribution exhibits a power-law dependence in the small size limit, $P(R)\sim R^{\alpha-1}$.
A. Yokoyama   +27 more
core   +1 more source

Establishment of a continuous sonocrystallization process for lactose in an oscillatory baffled crystallizer [PDF]

open access: yes, 2015
Crystallization at production scale (>10 kg) is typically a poorly understood unit operation with limited application of first-principles understanding of crystallization to routine design, optimization, and control.
Brown, Cameron J.   +3 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Aplicación de métodos matemáticos y estadísticos en la industria The application of mathematical and statistical methods in industry

open access: yesRevista Técnica de la Facultad de Ingeniería, 2010
La Quimiometría ha sido definida como “la disciplina que utiliza métodos matemáticos y estadísticos para seleccionar o diseñar procedimientos y experimentos óptimos, y proveer información relevante a partir de datos químicos”.
Carlos Alciaturi   +3 more
doaj  

Process analytical technology tools for perfusion cell culture

open access: yesEngineering in Life Sciences, 2016
During cell cultivation processes for the production of biopharmaceuticals, good process performance and good product quality can be ensured by online monitoring of critical process parameters (e.g. temperature, pH, or dissolved oxygen).
Sarah M. Mercier   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Neural Network-Based Kinetic Model for Antisolvent Crystallization of Benzophenone: Construction, Validation, and Mechanistic Interpretation

open access: yesCrystals
The emergence of artificial neural networks and the widespread application of process analytical technology (PAT) have founded a robust foundation for neural network applications in crystallization research.
Yafei Dong   +5 more
doaj   +1 more source

A BRIEF REVIEW ON PROCESS ANALYTICAL TECHNOLOGY (PAT) [PDF]

open access: yes, 2016
Process analytical technology (PAT) has been defined as a mechanism to design, analyze and control pharmaceutical manufacturing processes through measurement of critical process parameters which affect critical quality attributes.
Jagtap, Monali   +3 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Towards a theoretical foundation of IT governance: the COBIT 5 case [PDF]

open access: yes, 2015
: COBIT, (Control Objectives for Information and Information related Technologies) as an IT governance framework is well-known in IS practitioners communities. It would impair the virtues of COBIT to present it only as an IT governance framework.
Devos, Jan, Van De Ginste, Kevin
core  

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