Results 51 to 60 of about 138,359 (312)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Food intakes based on degree of processing and metabolic dysfunction-associated steatotic liver disease (MASLD): the Tehran Lipid and Glucose Study (TLGS)

Nutrition & Metabolism
Background Current evidence on the association between food processing and metabolic dysfunction-associated steatotic liver disease (MASLD) is limited to the intake of ultra-processed food (UPF). We investigated the associations between different degrees
Nazanin Moslehi, Farhad Hosseinpanah, Parvin Mirmiran, Fereidoun Azizi   +3 more
doaj   +1 more source

Socio-economic difference in purchases of ultra-processed foods in Australia: an analysis of a nationally representative household grocery purchasing panel

International Journal of Behavioral Nutrition and Physical Activity, 2022
Background Consumption of ultra-processed foods is associated with increased risk of obesity and non-communicable diseases. Little is known about current patterns of ultra-processed foods intake in Australia.
Daisy H. Coyle, Liping Huang, Maria Shahid, Allison Gaines, Gian Luca Di Tanna, Jimmy Chun Yu Louie, Xiongfei Pan, Matti Marklund, Bruce Neal, Jason H. Y. Wu   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Consumption of ultra-processed foods and socioeconomic position: a cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health

Cadernos de Saúde Pública, 2018
The objective of the study was to estimate the contribution of ultra-processed foods to total caloric intake and investigate whether it differs according to socioeconomic position.
Bárbara dos Santos Simões, Letícia de Oliveira Cardoso, Isabela Judith Martins Benseñor, Maria Inês Schmidt, Bruce Bartholow Duncan, Vivian Cristine Luft, Maria del Carmen Bisi Molina, Sandhi Maria Barreto, Renata Bertazzi Levy, Luana Giatti   +9 more
doaj   +1 more source

Informatics for Food Processing

ArXiv
This chapter explores the evolution, classification, and health implications of food processing, while emphasizing the transformative role of machine learning, artificial intelligence (AI), and data science in advancing food informatics. It begins with a historical overview and a critical review of traditional classification frameworks such as NOVA ...
Gordana Ispirova, Michael Sebek, Giulia Menichetti   +2 more
openaire   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Longitudinal changes in processed food intake and their daily caloric contribution among Ghanaian populations living in Ghana and Europe: findings from the prospective Research on Obesity and Diabetes among African Migrants (RODAM) cohort study

BMC Global and Public Health
Background Dietary changes towards increased consumption of processed and ultra-processed foods are major contributors to obesity and non-communicable diseases worldwide. However, limited data exist on the intake of processed foods among Ghanaians living
Mustapha Titi Yussif, Reginald Adjetey Annan, Anthony Edusei, Mary Nicolaou, Erik Beune, Samuel Nkansah Darko, Ina Danquah, Karlijn A. C. Meeks, Ellis Owusu-Dabo, Charles Agyemang   +9 more
doaj   +1 more source

Phase angle is inversely related to the consumption of ultra-processed foods and positively related to the consumption of minimally processed foods by university students: a cross-sectional study

Public Health Nutrition
Objective: Ultra-processed foods (UPF) and minimally processed foods (MPF) consumption are differentially connected to adiposity and possibly body composition.
Paraskevi Detopoulou, Despoina Levidi, Olga Magni, Vassilios Dedes, Milia Tzoutzou, Evaggelia Fappa, Aristea Gioxari, Georgios Panoutsopoulos   +7 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source