Results 231 to 240 of about 73,102 (302)

Ischaemic stroke and 5‐fluorouracil or capecitabine: A systematic review and meta‐analysis of harms and a retrospective study of the WHO pharmacovigilance database

British Journal of Pharmacology, EarlyView.
Abstract Aim Fluoropyrimidines, including 5‐fluorouracil (5‐FU) and capecitabine, are cornerstone antineoplastic agents for cancer. Case reports suggest that these drugs may be associated with an under‐recognised risk of ischaemic stroke or transient ischaemic attack (TIA).
Sophie Nguyen, Ines Bentahrour, Camille Guerin, Charles Dolladille, Angélique Da Silva, François Cherifi, Elise‐Marie Minoc, Pierre‐Marie Morice, Nicolas Jacquin, Christophe Le Tourneau, Joachim Alexandre, Ahmad Nehme, Etienne Bastien   +12 more
wiley   +1 more source

Breaking the Limitations of 'Milk': Research Progress on New Derivatives of Propofol. [PDF]

Molecules
Huang L, Xia Y, Shi J, Chen Y, Hao C.
europepmc   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source

Gene therapy as an upcoming technique in the treatment of cancer: A cellular solution to a cellular problem. [PDF]

Mol Ther Oncol
Bedada AT, Genet S.
europepmc   +1 more source

Engineering a conditionally active cetuximab prodrug via affibody-based paratope masking. [PDF]

J Biol Eng
Mestre Borras A, Mehari H, Bitzios A, Zelepukin I, Ud-Din M, Xu T, Li S, Orlova A, Tolmachev V, Ståhl S, Vorobyeva A, Löfblom J.   +11 more
europepmc   +1 more source

Combinatorial Therapy with Long-Acting Tenofovir and Tizoxanide Controls Viral Replication and Liver Inflammation in a Murine AAV-HBV Model of Chronic Hepatitis B. [PDF]

Biology (Basel)
Ogunnaike MO, Sultana A, Raut S, Wang W, Bybee G, Gendelman HE, Edagwa BJ, Osna NA, Poluektova LY.   +8 more
europepmc   +1 more source

Hybrid Aminoferrocenes With Nitrate Esters for In Situ Peroxynitrite Generation: Complex Interplay Between Redox Chemistry, NO-Donor Reactivity, and Aminoferrocene Activation Influences In Vitro Anticancer Activity. [PDF]

Chembiochem
Özkan HG, Selin R, Holst P, Tietze R, Alexiou C, Mokhir A.   +5 more
europepmc   +1 more source

Design, synthesis and biological evaluation of a β-galactosidase-activated glycopeptide analogue of somatostatin. [PDF]

RSC Adv
O'Leary CJ, Corbezzolo S, Newton A, Benny A, Scanlan EM, Kolodziejczak K, Monaghan MG, McGouran JF.   +7 more
europepmc   +1 more source