Results 41 to 50 of about 6,311,964 (280)

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Collaborative Product Development [PDF]

, 2005
This chapter discusses the roles of electronic business solutions (EBSs) in supporting collaborative product development (CPD). Two fundamental questions are of primary interest. One is when and where EBSs should be applied for what CPD decision activities.
openaire   +2 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Investigation of manufacturing deviations of CPC scaffolds for improving the design process

Current Directions in Biomedical Engineering, 2023
In current implantology, calcium phosphate cement (CPC) is increasingly used. A special focus is given to CPC scaffolds, as they are suitable for cell settlement and growth due to their positive osteoconductive properties.
Seidler Alexander, Pendzik Martin, Hilbig Arthur, Sembdner Philipp, Holtzhausen Stefan, Paetzold-Byhain Kristin   +5 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Evaluation of QT Liability for PF‐05251749 in the Presence of Potential Circadian Rhythm Modification

CPT: Pharmacometrics & Systems Pharmacology, 2020
PF‐05251749 is a dual inhibitor of casein kinase 1 δ/ε, key regulators of circadian rhythm. As a result of its mechanism of action, PF‐05251749 may also change the heart rate corrected QT (QTc) circadian rhythm, which may confound detection of drug ...
Yeamin Huh, Danny Chen, Steve Riley, Cheng Chang, Timothy Nicholas   +4 more
doaj   +1 more source

Sustainable product development strategies: Business planning and performance implications [PDF]

, 2012
Copyright © 2012 by Institution of Mechanical Engineers. This is the author's accepted manuscript. The final published article is available from the link below.Manufacturing firms are under many financial and competitive pressures which focus attention ...
Aurich JC, Davis S, Jacques JJ, McDonough W, Piller FT, Pine BJ, Toffler A   +6 more
core   +1 more source

Type 1 interferon mediated signaling is indispensable for eliciting anti-tumor responses by Mycobacterium indicus pranii

Frontiers in Immunology, 2023
IntroductionThe evolving tumor secretes various immunosuppressive factors that reprogram the tumor microenvironment (TME) to become immunologically cold.
Gargi Roy, Anush Chakraborty, Bharati Swami, Lalit Pal, Charvi Ahuja, Soumen Basak, Sangeeta Bhaskar   +6 more
doaj   +1 more source

Towards a New Framework for Product Development [PDF]

, 2000
In the mid-1980s, Andreasen and Hein first described their model of Integrated Product Development. Many Danish companies quickly embraced the principles of integrated product development and adapted the model to their specific business and product ...
McAloone, TC, Robotham, AJ
core   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source