Results 81 to 90 of about 6,311,964 (280)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Long term sustainable product development at the packaging sector [PDF]

open access: yes, 2011
This paper outlines the importance of sustainable product developments and their role in securing a sustainable future through current practices and procedures.
Cheung, Wai Ming   +3 more
core  

Characterizing the development of sectoral Gross Domestic Product composition

open access: yes, 2013
We consider the sectoral composition of a country's GDP, i.e. the partitioning into agrarian, industrial, and service sectors. Exploring a simple system of differential equations we characterize the transfer of GDP shares between the sectors in the ...
Kropp, Jürgen P.   +4 more
core   +1 more source

A Consumer-Centric Open Innovation Framework for Food and Packaging Manufacturing [PDF]

open access: yes, 2015
This article has been archived following written permission from IGI Global.Closed innovation approaches have been employed for many years in the food industry.
Baurley, S   +7 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Application of Tiling Theory for Path Planning Strategy in a Polyiamond Inspired Reconfigurable Robot

open access: yesIEEE Access, 2019
Commercial floor cleaning robots face significant challenges in accessing convex and narrow corners due to their fixed and regular morphologies. To overcome this, we develop a new class of self-reconfigurable floor cleaning robot, hTetrakis, which is ...
Rizuwana Parween   +4 more
doaj   +1 more source

Reengineering Biomedical Engineering Curricula: A New Product Development Approach [PDF]

open access: yes, 2002
Product development engineers in medical industries have created design control procedures to ensure high quality designs that are as error-free as possible.
Ropella, Kristina M.   +2 more
core   +1 more source

SMEs; Virtual research and development (R&D) teams and new product development: A literature review [PDF]

open access: yes, 2010
Small and medium-sized enterprises (SMEs) are indeed the engines of global economic growth. Their continued growth is a major subject for the economy and employment of any country.
Ahmed, Shamsuddin   +2 more
core   +6 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Integrating computational simulation and high-throughput screening for the development of robust ultra-high concentration formulation of IgG1 antibody

open access: yesmAbs
High-viscosity monoclonal antibody (mAb) formulations impede injection, complicate manufacturing, and may affect drug stability and patient outcomes. Nevertheless, these issues can be effectively mitigated through the judicious selection of appropriate ...
Chen Lyu   +13 more
doaj   +1 more source

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