Results 101 to 110 of about 3,167,450 (250)

STRATEGIC PATENT BREADTH FOR DRASTIC PRODUCT INNOVATIONS [PDF]

open access: yes
The paper models the patenting behavior of the innovator/patent applicant who having invented a drastic product innovation decides on the optimal breadth of protection claimed. The patenting process is modeled as a sequential game of complete information.
Yiannaka, Amalia, Fulton, Murray E.
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Realizing Innovations in Service Firms: new organizational forms and supporting processes [PDF]

open access: yes
This paper describes a number of innovation forms that are of special relevance to firms in the service industry. Not only technological innovations but also organizational innovations have been distinguished.
Elfring, T., Aa, W. van der
core  

Relationship between eco-innovations and the impact on business performance: an empirical survey research on the Brazilian textile industry

open access: yesRAUSP: Revista de Administração da Universidade de São Paulo
This study draws from the resource-based theory and investigates the interrelationships between three types of eco-innovation (process, product, organizational) and their impact on business performance.
Marcus Vinicius de Oliveira Brasil   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Buyer Power and Product Innovation: Empirical Evidence from the German Food Sector. [PDF]

open access: yes
Substantial increases in retail concentration (particularly in Europe) raise concerns about the welfare implications for consumers. In a formal model, we argue that retailer market power reduces upstream firms incentives to introduce new products. On the
Weiss, Christoph R., Wittkopp, Antje
core  

Market of innovations in composition of the innovative infrastructure of country [PDF]

open access: yesMarketing i Menedžment Innovacij, 2015
The aim of the article is to research processes of functioning the market of innovations and the identification of its further development as a part of innovation infrastructure. The results of the analysis.
A.A. Knyazevich
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The Determinants of Environmental Innovations and Patenting: Germany Reconsidered [PDF]

open access: yes
This paper provides new evidence on the objectives and determinants of different typesof innovations and patents, environmental as opposed to other innovations and patents,and different variants of environmental innovations and patents.
Frank Goetzke, Tilmann Rave, Mario Larch
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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