Do Spillovers Stimulate Incremental or Drastic Product Innovations? Hypotheses and Evidence from German Establishment Data [PDF]
We estimate the determinants of various types of product innovation. Knowledge spillovers from rivals have a positive impact on incremental innovations. This impact is largely independent of the participation in R&D cooperations. Spillovers exert no such
Jirjahn, Uwe, Kraft, Kornelius
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
"How to Measure the Outcome of Innovations: Application to Product Innovations" [PDF]
This paper provided a conceptual framework to quantify consumer gains from product innovations. Using an example of VCRs, we illustrate a model that is useful to measure consumer welfare, and describe what data are to be used for the analysis.
Hiroshi Ohashi
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Data-Driven Business Innovation Processes: Evidence from Authorized Data Flows in China
SystemsThe importance of data in current societal activities cannot be overstated, yet we know little about data governance and application. Using the Chinese Government Data Empowerment Initiative, this paper examines the process of data-driven business ...
Xueyuan Gao, Hua Feng
doaj +1 more source
Harnessing the Potential of Emerging Technologies: A Review of Key Development and Commercialization Strategies [PDF]
Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2004 Emerging technologies such as biotheraputics are widely view as the source of new types of competitive advantage. Despite their huge potential gaining advantages from these technologies requires adopting different types of managerial skills and insight ...
Kamran Feizi, Alfred Sarkissian
doaj
Consultants and firm-level innovation performances: a doubly robust estimation approach [PDF]
Eastern Journal of European Studies, 2020 This paper examines firms use of external consultants and commercial labs as an essential source of knowledge for innovation performance and activities in the IT and other information service firms.
Samuel AMPONSAH ODEI +2 more
doaj
Product Innovation and Growth: The Case of Integrated Circuits. [PDF]
Applied research on growth and innovation seems to suggest that successful innovations do not significantly enhance firm growth. This paper tests the hypothesis that the level of observation at which applied research is typically conducted hampers ...
Marco Corsino
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Lifecycle management of product innovations in enterprises considering stage-specific risks [PDF]
Економічний вісник Державного вищого навчального закладу Український державний хіміко-технологічний університетThis article is dedicated to developing methodological foundations for managing the lifecycle of product innovations in enterprises, with particular attention to the risks associated with each stage.
Sergii Illiashenko +3 more
doaj +1 more source