Results 91 to 100 of about 760,836 (304)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
SPILLOVERS IN PRODUCT AND PROCESS INNOVATION: EVIDENCE FROM MANUFACTURING FIRMS [PDF]
This paper proposes a new empirical approach to assess the impact of knowledge spillovers on firms' productivity and demand. I consider a model where process innovations spillovers to other firms raise firms relative efficiency and technological ...
Carmine Ornaghi
core +3 more sources
Russian Journal of Economics and Law, 2011 The work specifies the apparatus criticus of elaboration of ecology-oriented technological innovations, presents the topical types and techniques of assessment of product and procedural ecology-oriented innovations, improves the model of forming product ...
E. Shaimiyeva
doaj
Environmental innovations and sustainability practices of manufacturing firms in Uganda [PDF]
Asia Pacific Journal of Innovation and EntrepreneurshipPurpose – The purpose of this study is to investigate the pivotal role of environmental innovations in driving sustainability practices within medium and large manufacturing firms operating in Uganda. Design/methodology/approach – Using a cross-sectional
Kassim Alinda +2 more
doaj +1 more source
The Determinants and Effects of Environmental Product Innovations - An Analysis on the Basis of Case Studies [PDF]
The aim of the Integrated Product Policy (IPP) is to promote product-related eco-innovations. These, in turn, depend on both support for the development of environmentally-friendly products and stimulation of demand for such products.
Tuerpitz, Katharina
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Possibilities of innovative development of the company in business model construction
Путеводитель предпринимателя, 2020 Innovations are connected about uncertainty and risk as the effect from their introduction has, as a rule, long-term character and is connected with bigfinancial expenses.
M. A. Yakhjyaev, B. R. Shakirtkhanov
doaj
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
IMPACT OF INNOVATIONS ON THE PRODUCT MARKET COMPETITIVE DEVELOPMENT
International Journal of Innovative Technologies in Economy, 2018 Competitive product markets are characterized by aiming at complete consumers’ needs satisfaction, flexible market price making, freedom of economic activity and entrepreneurship, free entry and exit from a market, fair trading and business practices etc.
Zhanna Poplavska +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source