Results 91 to 100 of about 103,011 (308)

Are Exporters More Likely to Introduce Product Innovations? [PDF]

open access: yes
A firm\'s export status may improve its capacity of introducing product innovations. We explore this idea using very rich firm-level data on Italian A firm\'s export status may improve its capacity of introducing product innovations. We explore this idea
Giulia Felice, Massimiliano Bratti
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Diffusion Dynamics of Sustainable Innovation - Insights on Diffusion Patterns Based on the Analysis of 100 Sustainable Product and Service Innovations

open access: yesJournal of Innovation Management, 2016
There is a growing consensus about the urgent necessity to green the economy and to decouple economic growth from environmental pressure. Against this background, the article explores three questions: (1) What are key factors influencing diffusion ...
Klaus Fichter, Jens Clausen
doaj   +1 more source

Vaccine innovation prioritisation strategy: Findings from three country-stakeholder consultations on vaccine product innovations. [PDF]

open access: yesVaccine, 2021
Mvundura M   +12 more
europepmc   +1 more source

Understanding consumer needs and preferences in new product development: the case of functional food innovations [PDF]

open access: yes
As the majority of new products fail it is important to focus on the needs and preferences of the consumers in new product development. Consumers are increasingly recognised as important co-developers of innovations, often developing new functions for ...
Rogier Donders, Ellen H.M. Moors
core  

Critical factors for implementing and diffusing sustainable Product-Service Systems: Insights from innovation studies and companies' experiences [PDF]

open access: yes, 2013
This is the post-print version of the final paper published in Journal for Cleaner Production. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Ceschin, F
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Adoption of Product and Process Innovations in Differentiated [PDF]

open access: yes
The paper examines the effects of the degree of competition on the firms' decision to innovate in differentiated markets. We find that a low (high) degree of product differentiation (competition) weakly supports the introduction of new products.
Pia Weiss
core  

The effect of innovation activity on innovating quasi-rents: an empirical application [PDF]

open access: yes, 1998
This paper investigates whether innovations generate quasi-rents and whether the size of those quasi-rents are affected by market conditions. Using a panel data of Spanish manufacturing firms during the period 1990-93 we answer affinnatevely to both ...
Martínez-Ros, Ester   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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