Results 91 to 100 of about 3,167,450 (250)
Data-Driven Business Innovation Processes: Evidence from Authorized Data Flows in China
SystemsThe importance of data in current societal activities cannot be overstated, yet we know little about data governance and application. Using the Chinese Government Data Empowerment Initiative, this paper examines the process of data-driven business ...
Xueyuan Gao, Hua Feng
doaj +1 more source
Lifecycle management of product innovations in enterprises considering stage-specific risks [PDF]
Економічний вісник Державного вищого навчального закладу Український державний хіміко-технологічний університетThis article is dedicated to developing methodological foundations for managing the lifecycle of product innovations in enterprises, with particular attention to the risks associated with each stage.
Sergii Illiashenko +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The Protection of Innovations [PDF]
This paper proposes a model where firms invest in secrecy to limit technological spillovers accruing to their competitors, in addition to investing in cost-reducing R&D.
Gamal Atallah
core
Consultants and firm-level innovation performances: a doubly robust estimation approach [PDF]
Eastern Journal of European Studies, 2020 This paper examines firms use of external consultants and commercial labs as an essential source of knowledge for innovation performance and activities in the IT and other information service firms.
Samuel AMPONSAH ODEI +2 more
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Licensing radical product innovations to speed up the diffusion [PDF]
Inventors can commercialize innovative products by themselves and simultaneously license the technology to other firms. The licensee may cannibalize sales of the licensor, but this can be compensated by gains from royalties.
Mercedes Esteban Bravo +2 more
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
"How to Measure the Outcome of Innovations: Application to Product Innovations" [PDF]
This paper provided a conceptual framework to quantify consumer gains from product innovations. Using an example of VCRs, we illustrate a model that is useful to measure consumer welfare, and describe what data are to be used for the analysis.
Hiroshi Ohashi
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source