Results 81 to 90 of about 760,836 (304)

Vaccine innovation prioritisation strategy: Findings from three country-stakeholder consultations on vaccine product innovations. [PDF]

open access: yesVaccine, 2021
Mvundura M   +12 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Diffusion Dynamics of Sustainable Innovation - Insights on Diffusion Patterns Based on the Analysis of 100 Sustainable Product and Service Innovations

open access: yesJournal of Innovation Management, 2016
There is a growing consensus about the urgent necessity to green the economy and to decouple economic growth from environmental pressure. Against this background, the article explores three questions: (1) What are key factors influencing diffusion ...
Klaus Fichter, Jens Clausen
doaj   +1 more source

Innovations in the biodiesel production

open access: yesPressacademia, 2017
Demand on energy from alternative fuels are growing rapidly due to depletion of fossil fuels and global warming crises. Biodiesel instead of conventional petroleum diesel, is a non toxic, biodegradable and renewable fuels.  Therefore, biodiesel can be considered as a promising liquid fuel for transport sector.
Cakirca, Emine Emel, Akin, Ayse Nilgun
openaire   +3 more sources

Effects of organizational innovations on firm's production performance [PDF]

open access: yes, 2008
In the literature, various papers investigate the effects of the technological (product and process) innovations on firms performance. However, research on the effects of organizational innovations is rare.
Alpkan, Lutfihak   +7 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Exploring the Enablers of Organizational and Marketing Innovations in SMEs

open access: yesSAGE Open, 2015
Previous research studies on innovation tend to focus on process and product innovations. Recent theoretical opinions reveal that Organizational and Marketing Innovations (OMIs) could be the necessary prerequisites to optimally utilize and deploy such ...
Oluseyi Moses Ajayi, Susan C. Morton
doaj   +1 more source

Does patenting increase the private incentives to innovate? A microeconometric analysis [PDF]

open access: yes
This paper examines whether patenting increases the private incentives to innovate in manufacturing. To study this issue, we build a model in which the value of an innovation depends both on the type of innovation implemented (product, process) and on ...
DUGUET Emmanuel, LELARGE Claire
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Do Process Innovations Induce Product Ones? [PDF]

open access: yes
We study the relationship between process and product innovations in vertically differentiated duopolies. A process innovation can lead two competing firms to improve the quality of their goods introducing a product innovation.
Maria Rosa Battaggion, Piero Tedeschi
core  

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