Results 141 to 150 of about 3,314 (190)
Regulation of Striatonigral Prodynorphin Peptides by Dopaminergic Agents [PDF]
Brain Research, 1990 The primary purpose of this study was to examine the regulation of prodynorphin peptides by dopaminergic agents in the central nervous system. The indirectly acting catecholamine agonist D-amphetamine sulfate (AMPH) and the dopamine receptor antagonist haloperidol (HAL) were administered to rats across a variety of treatment schedules and drug doses ...
Robert Day, Keith A. Trujillo, Huda Akil
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Prodynorphin mRNA Expression in Adult Cultured Rat Ventricular Cardiac Myocytes
Biochimica Et Biophysica Acta Gene Regulatory Mechanisms, 1993 Prodynorphin mRNA was synthesized both in rat atrial and ventricular tissue, as well as in adult cultured rat ventricular cardiac myocytes. In the cultured cells, the content of prodynorphin mRNA did not differ from that detected in the original ...
Santi Spampinato +2 more
exaly +2 more sources
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Peptides, 2006
The detection of the prodynorphin gene in anuran amphibians and lungfishes may indicate that this gene arose as a result of the duplication of the proenkephalin gene early during the divergence of the Sarcopterygii, or that this gene may predate the divergence of the ray-finned fish and the lobe-finned fish.
Stephanie Lécaudé +2 more
exaly +3 more sources
The detection of the prodynorphin gene in anuran amphibians and lungfishes may indicate that this gene arose as a result of the duplication of the proenkephalin gene early during the divergence of the Sarcopterygii, or that this gene may predate the divergence of the ray-finned fish and the lobe-finned fish.
Stephanie Lécaudé +2 more
exaly +3 more sources
General and Comparative Endocrinology, 2012
Analyses of prodynorphin and proenkephalin cDNAs cloned from the central nervous system of the shark, Heterodontus portusjacksoni, provided additional evidence that these two opioid precursor-coding genes were most likely directly derived from a common ancestral gene. The two cDNAs could be aligned by inserting only seven gaps.
Phillip B Danielson
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Analyses of prodynorphin and proenkephalin cDNAs cloned from the central nervous system of the shark, Heterodontus portusjacksoni, provided additional evidence that these two opioid precursor-coding genes were most likely directly derived from a common ancestral gene. The two cDNAs could be aligned by inserting only seven gaps.
Phillip B Danielson
exaly +3 more sources
Molecular Brain Research, 1997
We have characterized a prodynorphin-like molecule in an invertebrate, specifically in the rhynchobdellid leech Theromyzon tessulatum. The 14270 Da protein was purified by gel permeation chromatography, anti-leucine-enkephalin-affinity column separation followed by reverse-phase HPLC.
George Stefano, Michel Salzet
exaly +3 more sources
We have characterized a prodynorphin-like molecule in an invertebrate, specifically in the rhynchobdellid leech Theromyzon tessulatum. The 14270 Da protein was purified by gel permeation chromatography, anti-leucine-enkephalin-affinity column separation followed by reverse-phase HPLC.
George Stefano, Michel Salzet
exaly +3 more sources
Mytilus edulis Hemolymph Contain Prodynorphin
Immunology Letters, 1998We have characterized a prodynorphin (prodyn) molecule in hemocytes and hemolymph of the bivalve mollusk Mytilus edulis. The ca. 16-kDa protein was purified by cut-off filtration prepurification, anti-leucine-enkephalin affinity column separation followed by reversed-phase HPLC.
George Stefano, Michel Salzet
exaly +3 more sources
cDNA sequence and expression of bovine prodynorphin
Gene, 1997Prodynorphin (ProDYN) in the anterior pituitary gland appears to be processed differently from the brain, and the ProDYN-derived peptides may function differently in the anterior pituitary than in the brain. To further investigate the roles of ProDYN-derived peptides in the anterior pituitary, we have determined the nucleotide (nt) sequence of the cDNA
H, Jiang, G D, Weesner, P V, Malven
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Proenkephalin and prodynorphin related neuropeptides in the cochlea
Hearing Research, 1985Dynorphin B (rimorphin), a proenkephalin B (prodynorphin)-derived peptide, and met-enkephalin-Arg6, Gly7, Leu8 (met-enkephalin octapeptide), a proenkephalin A-derived peptide, were identified in the mammalian cochlea by specific radioimmunoassays. The antisera are directed against unique sequences in the peptides, and this immunoreactivity cannot be ...
D W, Hoffman +4 more
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Characterization of Human Prodynorphin Gene Transcripts
Biochemical and Biophysical Research Communications, 1995Prodynorphin gene transcripts have been characterized in human tissues with cRNA probes covering parts of the non-coding exon 1 and the main coding exon 4 using Northern blot and RNase protection experiments. A 2.8-kb signal was observed in human brain RNA with both the exon 1 and exon 4 probes.
T, Geijer, M, Telkov, L, Terenius
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