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Regulation of striatonigral prodynorphin peptides by dopaminergic agents [PDF]
The primary purpose of this study was to examine the regulation of prodynorphin peptides by dopaminergic agents in the central nervous system. The indirectly acting catecholamine agonist D-amphetamine sulfate (AMPH) and the dopamine receptor antagonist haloperidol (HAL) were administered to rats across a variety of treatment schedules and drug doses ...
Robert Day, Keith Trujillo
exaly +6 more sources
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Molecular Brain Research, 1997
We have characterized a prodynorphin-like molecule in an invertebrate, specifically in the rhynchobdellid leech Theromyzon tessulatum. The 14270 Da protein was purified by gel permeation chromatography, anti-leucine-enkephalin-affinity column separation followed by reverse-phase HPLC.
George Stefano, Michel Salzet
exaly +3 more sources
We have characterized a prodynorphin-like molecule in an invertebrate, specifically in the rhynchobdellid leech Theromyzon tessulatum. The 14270 Da protein was purified by gel permeation chromatography, anti-leucine-enkephalin-affinity column separation followed by reverse-phase HPLC.
George Stefano, Michel Salzet
exaly +3 more sources
General and Comparative Endocrinology, 2012
Analyses of prodynorphin and proenkephalin cDNAs cloned from the central nervous system of the shark, Heterodontus portusjacksoni, provided additional evidence that these two opioid precursor-coding genes were most likely directly derived from a common ancestral gene. The two cDNAs could be aligned by inserting only seven gaps.
Phillip B Danielson
exaly +3 more sources
Analyses of prodynorphin and proenkephalin cDNAs cloned from the central nervous system of the shark, Heterodontus portusjacksoni, provided additional evidence that these two opioid precursor-coding genes were most likely directly derived from a common ancestral gene. The two cDNAs could be aligned by inserting only seven gaps.
Phillip B Danielson
exaly +3 more sources
Mytilus edulis hemolymph contain prodynorphin
Immunology Letters, 1998We have characterized a prodynorphin (prodyn) molecule in hemocytes and hemolymph of the bivalve mollusk Mytilus edulis. The ca. 16-kDa protein was purified by cut-off filtration prepurification, anti-leucine-enkephalin affinity column separation followed by reversed-phase HPLC.
George Stefano, Michel Salzet
exaly +3 more sources
Prodynorphin mRNA expression in adult cultured rat ventricular cardiac myocytes
Prodynorphin mRNA was synthesized both in rat atrial and ventricular tissue, as well as in adult cultured rat ventricular cardiac myocytes. In the cultured cells, the content of prodynorphin mRNA did not differ from that detected in the original ...
Santi Spampinato +2 more
exaly +2 more sources
Peptides, 2006
The detection of the prodynorphin gene in anuran amphibians and lungfishes may indicate that this gene arose as a result of the duplication of the proenkephalin gene early during the divergence of the Sarcopterygii, or that this gene may predate the divergence of the ray-finned fish and the lobe-finned fish.
Jasem, Alrubaian +9 more
exaly +3 more sources
The detection of the prodynorphin gene in anuran amphibians and lungfishes may indicate that this gene arose as a result of the duplication of the proenkephalin gene early during the divergence of the Sarcopterygii, or that this gene may predate the divergence of the ray-finned fish and the lobe-finned fish.
Jasem, Alrubaian +9 more
exaly +3 more sources
Ontogeny of prodynorphin gene expression in the rat hypothalamus
Developmental Brain Research, 1993Opioid peptides, deriving from prodynorphin, proenkephalin and proopiomelanocortin genes, have been shown to modulate brain development. Prodynorphin gene expression was studied here by in situ hybridization in the developing rat hypothalamus using oligodeoxynucleotide probes.
J M Felix, M E Stoeckel, F René
exaly +3 more sources
cDNA sequence and expression of bovine prodynorphin
Gene, 1997Prodynorphin (ProDYN) in the anterior pituitary gland appears to be processed differently from the brain, and the ProDYN-derived peptides may function differently in the anterior pituitary than in the brain. To further investigate the roles of ProDYN-derived peptides in the anterior pituitary, we have determined the nucleotide (nt) sequence of the cDNA
H, Jiang, G D, Weesner, P V, Malven
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Proenkephalin and prodynorphin related neuropeptides in the cochlea
Hearing Research, 1985Dynorphin B (rimorphin), a proenkephalin B (prodynorphin)-derived peptide, and met-enkephalin-Arg6, Gly7, Leu8 (met-enkephalin octapeptide), a proenkephalin A-derived peptide, were identified in the mammalian cochlea by specific radioimmunoassays. The antisera are directed against unique sequences in the peptides, and this immunoreactivity cannot be ...
D W, Hoffman +4 more
openaire +2 more sources

