Acute cocaine treatment increases thimet oligopeptidase in the striatum of rat brain [PDF]
, 2012 Many studies indicate that thimet oligopeptidase (EC3.4.24.15; TOP) can be implicated in the metabolism of bioactive peptides, including dynorphin 1-8, alpha-neoendorphin, beta-neoendorphin and GnRH.
Andersen, Monica Levy +13 more
core +1 more source
Stress alters hypothalamic gene expression in adolescent male Golden hamsters
Journal of Neuroendocrinology, Volume 37, Issue 9, September 2025.Abstract In Golden hamsters (Mesocricetus auratus), a two‐week exposure to chronic social stress in adolescence causes acceleration of agonistic behavior, enhanced adult aggression, impaired waiting impulsivity, and higher food intake, body fat, and long‐term increased body weight.
Kevin M. Moran +3 more
wiley +1 more source
Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons. [PDF]
PLoS ONE, 2009 The widespread distribution of the tumor suppressor PTEN in the nervous system suggests a role in a broad range of brain functions. PTEN negatively regulates the signaling pathways initiated by protein kinase B (Akt) thereby regulating signals for growth,
Oscar Diaz-Ruiz +7 more
doaj +1 more source
Effects of Static and Low‐Frequency Magnetic Fields on Gene Expression
Journal of Magnetic Resonance Imaging, Volume 62, Issue 2, Page 317-334, August 2025.Substantial research over the past two decades has established that magnetic fields affect fundamental cellular processes, including gene expression. However, since biological cells and subcellular components exhibit diamagnetic behavior and are therefore subjected to very small magnetic forces that cannot directly compete with the viscoelastic and ...
Vitalii Zablotskii +3 more
wiley +1 more source
Crosstalk between astrocytic CXCL12 and microglial CXCR4 contributes to the development of neuropathic pain [PDF]
, 2016 published_or_final_versio
Cheung, CW +6 more
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International Endodontic Journal, Volume 58, Issue 8, Page 1126-1145, August 2025.Abstract Background Orthodontic forces may lead to neurogenic inflammation in the dental pulp by triggering the release of somatosensory neuropeptides such as Substance P (SP), Calcitonin gene‐related peptide (CGRP) and Neurokinin A (NKA). In the vast majority of patients, acute symptoms are not triggered, probably due to the control of the neurogenic ...
Javier Caviedes‐Bucheli +7 more
wiley +1 more source
Dopaminergic, glutamatergic but not opioidergic mechanisms mediate induction of FOS-like protein by cocaethylene [PDF]
, 1997 Cocaethylene is a psychoactive metabolite formed\ud during the combined consumption of cocaine and ethanol. As\ud this metabolite has many properties in common with cocaine, it is conceivable that cocaethylene administration may induce the activity of ...
DiPirro, Dr. J.M. +3 more
core
Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]
, 2013 Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
core +1 more source
Co-Localization of p-CREB and p-NR1 in Spinothalamic Neurons in a Chronic Muscle Pain Model [PDF]
, 2007 Activation of the cAMP pathway is an important mediator of chronic muscle pain. This study examined phosphorylation of the transcription factor cAMP-response-element-binding protein (p-CREB) and the NR1 subunit of the NMDA receptor (p-NR1) in the spinal ...
Bement, Marie K. Hoeger +1 more
core +2 more sources
Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]
, 2019 The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena +8 more
core +2 more sources